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Type: Adobe PDF
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Blob Bempedoic Acid a Small Molecule Drug Process and Syn...

Created: 2019-07-23 07:04:13

Credits: User Drkrishnasarmapathy

License: Creative Commons Attribution-Share Alike 3.0 Unported License

Low Density Lipoprotein Cholesterol AbstractBempedoic acid (ETC-1002), a small molecule drug, promotes low density lipoprotein (LDL) receptor mediated clearanceof LDL-cholesterol (LDL-C) by inhibition of adenosine triphosphate citrate lyase (ACL), a mechanism complementary to thoseof existing lipid-modifying therapies. Bempedoic acid is a pro-drug activated specifically within the liver where it inhibits ACL,a regulatory checkpoint within the cholesterol biosynthesis pathway. By inhibiti...

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Blob Crystallization and Polymorphism-Scalable Process fo...

Created: 2018-12-04 11:45:47

Credits: User Drkrishnasarmapathy

License: Creative Commons Attribution-Share Alike 3.0 Unported License

Crystallization and Polymorphism-Scalable Process for Celecoxib and It’s Polymorph From-3

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Blob Citation: Krishnasarma P, MS Chakravarthy. Crystalli...

Created: 2018-12-04 11:43:44

Credits: User Drkrishnasarmapathy

License: Creative Commons Attribution-Share Alike 3.0 Unported License

Citation: Krishnasarma P, MS Chakravarthy. Crystallization and Polymorphism-Scalable Process for Celecoxib and It’s Polymorph From-3(Non- Steroidal Anti-Inflammatory Drug (NSAID). LOJ Med Sci 2(2)-2018. LOJMS.MS.ID.000134. 125Review ArticleCrystallization and Polymorphism-Scalable Process forCelecoxib and It’s Polymorph From-3 (Non- SteroidalAnti-Inflammatory Drug (NSAID) 

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Blob Cefpodoxime Proxetil and its By-Products: A Comparat...

Created: 2018-08-31 07:40:48

Credits: User Drkrishnasarmapathy

License: Creative Commons Attribution-Share Alike 3.0 Unported License

Cefpodoxime Proxetil and its By-Products: A Comparative Study as Per EP-7 Krishnasarma pathy*LOJ Med Sci 

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Blob Biomedical Journal of Scientific & Technical Research.

Created: 2018-08-31 06:24:53

Credits: User Drkrishnasarmapathy

License: Creative Commons Attribution-Share Alike 3.0 Unported License

Considerations for Successful Scale-Up to Tox Batches and Phase-Api (Bulk Drug substance)[*]       Krishnasarma pathy* DOI : 10.26717/BJSTR.2018.08.001662Biomedical Journal of Scientific & Technical Research.

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Blob Biomedical Journal of Scientific & Technical Researc...

Created: 2018-08-31 06:23:50

Credits: User Drkrishnasarmapathy

License: Creative Commons Attribution-Share Alike 3.0 Unported License

Considerations for Successful Scale-Up to Tox Batches and Phase-Api (Bulk Drug substance)[*]       Krishnasarma pathy* DOI : 10.26717/BJSTR.2018.08.001662Biomedical Journal of Scientific & Technical Research.

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Blob Case History-The Control of Impurities-A Critical Is...

Created: 2018-08-01 05:40:18

Credits: User Drkrishnasarmapathy

License: Creative Commons Attribution-Share Alike 3.0 Unported License

Case History-The Control of Impurities-A CriticalIssue to The Active Pharmaceutical Ingredient 

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Blob Case History-The Control of Impurities-A Critical Is...

Created: 2018-08-01 05:35:55

Credits: User Drkrishnasarmapathy

License: Creative Commons Attribution-Share Alike 3.0 Unported License

Case History-The Control of Impurities-A CriticalIssue to The Active Pharmaceutical Ingredient 

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Blob Distribución de metales pesados en sedimentos superf...

Created: 2018-07-29 18:42:42

Credits: User William Senior

License: Creative Commons Attribution-Share Alike 3.0 Unported License

La concentración total y las formas químicas de los metales pesados se determinaron en sedimentossuperficiales del Orinoco Medio, Venezuela, utilizando una solución 25% (v/v) de acidoacético/solución HNO3: HCl: HClO4 (3:2:1), espectrofotometría de absorción atómica con llama ytécnica de vapor en frio. El rango de los valores totales variaron entre 8871 a 116.759 μgFeg-1,102,45 a 469,44 μgMn g-1; 0,93 a 17,64 μgCu g-1; 4,4...

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Blob DISTRIBUCIÓN Y ESPECIACIÓN DE ALGUNOS METALES PESADO...

Created: 2018-07-29 18:31:20

Credits: User William Senior

License: Creative Commons Attribution-Share Alike 3.0 Unported License

Se evaluó la distribución y especiación de los metales pesados Cd, Ni, Mn y Cu en sedimentos superficiales de tres áreas geográficas del oriente del país ubicadas en la Bahía de Guanta-Pertigalete, estado Anzoátegui, Venezuela. Las muestras fueron recolectadas utilizando una draga Diez Laffont de 0,02 m2 de área. Los sedimentos fueron sometidos a un proceso de extracción por pasos para extraer las diferentes fracciones geoq...

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