File Entry: GGTase

Created: 2016-10-24 06:00:22
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Version created on: 2016-10-24 06:00:22


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Geranylgeranyltransferase type 1 or simply geranylgeranyltransferase is one of the three enzymes in the prenyltransferase group. In specific terms, Geranylgeranyltransferase (GGTase 1) adds a 20-carbon isoprenoid called a geranylgeranyl group to proteins bearing a CaaX motif:a four-amino acid sequence at the carboxyl terminal of a protein. Geranylgeranyltransferase inhibitors are being investigated as anti-cancer agents.


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Non-Information Resource URI: http://www.myexperiment.org/files/1695


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