File Entry: Parameter Estimation for Simulation of Glycolysis Pathway by Using an Improved Differential Evolution

Created: 2012-07-24 04:46:49
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Version created on: 2012-07-24 04:46:49


Information Description

 An improved differential evolution (DE) algorithm is proposed in

this paper to optimize its performance in estimating the germane parameters for
metabolic pathway data to simulate glycolysis pathway for Saccharomyces
cerevisiae. This study presents an improved algorithm of parameter sensitivity
test into the process of DE algorithm. The result of the improved algorithm is
testifying to be supreme to the others estimation algorithms. The outcomes from
this study promote estimating optimal kinetic parameters, shorter computation
time and ameliorating the precision of simulated kinetic model for the
experimental data.

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