Team A from CSC8308, Newcastle University, 2011
Created at: Thursday 17 March 2011 @ 12:16:21 (GMT)
Unique name: CSC8308_ATeam
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Created: 30/03/11 @ 20:45:57 | Last updated: 01/04/11 @ 12:45:26
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
Comparison of the genome of Bacillus anthracis to closely related strains will allow the discovery of proteins which may be involved in pathogenicity. Based on the biochemical pathways where the protein interacts, vaccines can be designed for these unique proteins. By gaining insight into the biochemical pathways that the unique proteins are involved in, the proteins can also be assessed for potential quality as vaccines. The key components of the vaccine finding system are the following: T...
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Created: 28/03/11 @ 11:57:51 | Last updated: 01/04/11 @ 12:28:38
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
Thresholds tab-delimited BLAST results to a certain percent identity.
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Created: 25/03/11 @ 20:06:13 | Last updated: 01/04/11 @ 12:40:56
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
The drug repurposing workflow system screens at least 20 bacterial proteomes against this set of proteins that are already being treated against using established drugs. By screening the bacterial proteomes it will be possible to find proteins of highly similar structure to those that are existing drug protein targets and so this will infer that it is highly likely that the drugs can be used as antimicrobials against these proteins of highly similar structure. Proteomes that will be screene...
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Created: 24/03/11 @ 19:49:43 | Last updated: 01/04/11 @ 12:26:27
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
The workflow parses uses the tab-delimited BLAST results to determine the unique proteins found in the target genome that have no similarity to the source genome.The workflow parses uses the blast results to determine the unique proteins found in the target genome that have no similairty to the source genome. Using these unique protein ids, and the original target protein fasta file, a fasta file of unique proteins is created.This workflow allows you to configure a BioMart query to fetch sequ...
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