User: Paul Fisher
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Name: Paul Fisher Joined: Thursday 26 July 2007 @ 16:46:52 (GMT) Last seen: Friday 11 May 2012 @ 14:17:47 (GMT) Email (public): Not specified Website: http://twitter.com/#!/paul_r_fisher Location: Manchester, United Kingdom |
Paul Fisher has been credited 267 times Paul Fisher has an average rating of: 4.6 / 5 (25 ratings in total) for their items |
I am currently employed by Astrazeneca. As a consequence, the workflows developed previously to this employment (before 5th September 2011) may no longer be supported.
Other contact details:
Not specifiedInterests:
Workflows
QTL analysis
Microarrays
Biological pathway analysis
In silico automation
Epilepsy
Alzheimers
Genome Sequencing
Disease gene identification
Field/Industry: Bioinformatics
Occupation/Role(s): Bioinformatics Scientist - Oncology
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Created: 01/09/11 @ 17:17:57 | Last updated: 01/09/11 @ 17:18:05
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This zip file contains a large number of Taverna 2 workflows that utilise the Ondex Web Service, for manipulating Ondex graphs.
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Created: 01/04/11 @ 09:12:28 | Last updated: 01/04/11 @ 09:12:40
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Attributions: License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a list processed for Human gene expression CEL files relating to the: Impact of NRSF variant over-expression in SK-N-AS human neuroblastoma cells (http://www.ebi.ac.uk/arrayexpress/browse.html?keywords=E-GEOD-22467&expandefo=on).
The CEL files were analysed using the MADAT Taverna workflow available on myExperiment:
http://www.myexperiment.org/workflows/2002.html
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Created: 01/04/11 @ 09:08:45 | Last updated: 01/04/11 @ 09:08:51 License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a list or affymetrix probest identifiers for Human gene expression data relating to the: Impact of NRSF variant over-expression in SK-N-AS human neuroblastoma cells (http://www.ebi.ac.uk/arrayexpress/browse.html?keywords=E-GEOD-22467&expandefo=on)
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Created: 30/03/11 @ 09:17:52 | Last updated: 30/03/11 @ 09:17:55
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
Taverna training material for using and configuring XPath queries using native XPath Java methods, and XPath Service templates.
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Created: 28/03/11 @ 11:44:06 | Last updated: 28/03/11 @ 11:44:08
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
Training slides to outline how to use iterations and iteration strategies in Taverna
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Created: 28/03/11 @ 11:31:38 | Last updated: 28/03/11 @ 11:31:39
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
Agenda of Taverna training
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Created: 28/03/11 @ 11:29:08 | Last updated: 28/03/11 @ 11:29:10
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This powerpoint presentation contains a set of starting exercises for begining your Taverna training.
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Created: 23/03/11 @ 17:25:09 | Last updated: 23/03/11 @ 17:25:11
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains some example XML to be used for teaching material and XPath queries
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Created: 23/03/11 @ 17:00:58 | Last updated: 23/03/11 @ 17:01:01
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This powerpoint slide shows the how data in each flat file can be cross-reference to other flat file data items.
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Created: 23/03/11 @ 11:49:33 | Last updated: 23/03/11 @ 11:49:36
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This xml file conatins results from a pubmed search for 'Blood Clotting'.
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Created: 17/03/11 @ 11:21:06 | Last updated: 17/03/11 @ 11:21:12
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a list of all the SNP found with the Villard et al., (2002) QTL for Bilateral Perisylvian Polymicrogyria.
Please download this data as you wish, and use in whatever study you like. The data is open access, and freely available for all to use to help undertand this condition.
Genes related to these SNP can be found in the file http://www.myexperiment.org/files/466.
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Created: 17/03/11 @ 10:56:15 | Last updated: 17/03/11 @ 11:16:53
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This zip file contains the results of running a QTL workflow for Bilateral Perisylvian Polymicrogyria in human (homo sapiens). Provided are a list of candidate QTL genes (QTg) and their corresponding KEGG pathways. Each gene and pathway have been subsequently run through a series of text mining workflows to determine the significance each may play in relation to Bilateral Perisylvian Polymicrogyria.
If you want to help me identify candidate genes for this disorder, please get i...
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Created: 16/02/11 @ 15:16:17 | Last updated: 16/02/11 @ 15:16:24
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This zip file contains the results of workflow runs for: identifying genes in each of the 7 QTL regions for Trichuris muris infection; identifying genes differentially expressed in mice challenged with Trichuris muris; and Text mining results (including cosine vector scores and Term Enrichment values).
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Created: 07/12/10 @ 16:34:31 | Last updated: 07/12/10 @ 16:34:37
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This zip file contains the results of running a QTL workflow for Bilateral Perisylvian Polymicrogyria in human (homo sapiens). Provided are a list of candidate QTL genes (QTg) and their corresponding KEGG pathways. Each gene and pathway have been subsequently run through a series of text mining workflows to determine the significance of each may play in relation to Bilateral Perisylvian Polymicrogyria AND/OR Epilepsy. Further to this, I have also collected the SNPs (single nucleotide...
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Created: 02/11/09 @ 16:15:39 | Last updated: 02/11/09 @ 16:15:57
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a list of KEGG compounds which are reffered to by their Inchi strings.
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Created: 22/10/09 @ 13:50:53 | Last updated: 22/10/09 @ 13:51:51
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
Biological Data Integration Using Ondex and Taverna: A Tutorial
25/26th November 2009
The University of Manchester
The Ondex SABR project (http://ondex.org/sabr.html) invite you to a two-day tutorial that aims to show participants how to use Ondex and Taverna to perform common biological data collection, integration and visualisation tasks.
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Created: 11/08/09 @ 14:23:49
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a list of each pathway identified from day 7 post infection and linked to the Tir1 QTL. With each pathway is a list of terms that are common to both pathway and phenotype corpora. These terms were ranked accoring to their enrichement scores. The higher the score, the more significant the term is in relation to correlating the pathway with the African trypanosomiasis resistance phenotype.
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Created: 11/08/09 @ 14:08:41 | Last updated: 11/08/09 @ 14:15:58
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains all the abstracts for pathways found to be differentially expressed at day 7 post infection and intersect the Tir1 QTL region, from the African Trypanosomiasis project.
Each pathway is listed as ">> [Pathway Name]", together with a PubMed identifier, date, and abstract for each article. Each pathway has been restricted to 500 abstracts, and is given in the date range 31/12/2007 to 01/01/2009. Note, some pathways do not have any abstracts available due to th...
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Created: 11/08/09 @ 13:59:35
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a count of each phenotype term extracted from corpus of phenotype abstracts. Each value represents the number of articles in MEDLINE the term appears. The use of this file is to calculate a cosine vector score for correlating a given concept (e.g. pathway or gene) with a phenotype.
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Created: 11/08/09 @ 13:54:45
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains the number of articles available in MEDLINE, through PubMed, at the time of performing these data analyses. The date of identifying these publications was 25/02/2009.
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Created: 11/08/09 @ 13:34:42 | Last updated: 11/08/09 @ 13:58:28
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a count of each phenotype term extracted from corpus of phenotype abstracts. Each value represents the number of articles in the phenotype corpus the term appears. The use of this file is to calculate a cosine vector score for correlating a given concept (e.g. pathway or gene) with a phenotype.
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Created: 11/08/09 @ 13:05:07 | Last updated: 11/08/09 @ 13:06:51
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a list of all terms extracted from the phenotype corpus, relating to African trypanosomiasis resistance in the mouse model.
These terms were extracted using the following service: http://gopubmed4.biotec.tu-dresden.de/GoPubMedTermGenerationService/services/GoPubMedTermGeneration?wsdl
These terms represent the concept profile for the phenotype.
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Created: 11/08/09 @ 12:45:24
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a list of published abstracts from MEDLINE, that are related to the African Trypanosomiasis resistance phentoype in the mouse. The term used in the PubMed search was: trypanosom* AND (tolerance OR resistance) .
The workflow limited the date of the search using PubMed between 31/12/2005 to 01/01/2009, and was restricted to 500 abstracts.
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Created: 10/08/09 @ 16:00:45
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This excel file contains a list of genes linked to the resistance to African trypanosomiasis in the mouse. Genes from the Tir1 QTL were used in a search through PubMed. The results were then correlated to the trypanosomiasis resistance phenotype. The higher the score (and ranking) the more related to the phenotype the gene is likely to be. This is based on the co-occurrence of terms within the gene and phentoype corpora.
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Created: 10/08/09 @ 15:55:24
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This excel file contains a list of all pathways found to be differentially expressed at day 7 post infection in the trypanosomiasis resistance phenotype, which contain genes in the Tir1 QTL.
The pathways in this file have been ranked according to the scores obtained after calculating a cosine vector value against the trypanosomiasis resistance phenotype. The higher the score, the more closely linked to a phentype a given pathway is.
This allows each pathway to be ranked giving biologists a ...
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Created: 08/04/09 @ 19:30:15 | Last updated: 10/08/09 @ 11:05:59
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains all genes identified in the Tir1 QTL region.
Each gene is (if available) associated with an Entrez, UniProt, External Gene Id, Affymetrix probeset identifers (mouse_430_A chip), and Ensembl identifers for genes and their transcripts.
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Created: 08/04/09 @ 19:28:52 | Last updated: 10/08/09 @ 11:03:00
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a list of KEGG pathway identifiers, derived from a list of Ensembl genes found to be located with a given QTL/chromosomal region in the mouse. These genes are located in the Tir1 QTL.
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Created: 08/04/09 @ 19:27:55 | Last updated: 10/08/09 @ 11:29:34
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a list of KEGG pathway descriptions, identified from genes found within the Tir1 QTL region (for African Trypanosomiasis). Each pathway may contain multiple genes from within the QTL region.
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Created: 08/04/09 @ 19:26:26 | Last updated: 10/08/09 @ 11:41:55
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a list of all genes found within the Tir1 QTL region. These are represented as KEGG gene identifiers. Each gene is listed in tab deliminated format along with all KEGG pathway ids in which the gene is involved. These are given as KEGG pathway identifiers. Each gene may be included in zero or more pathways, with multiple instances of the same pathway being included in the file (due to multiple genes included in a single pathway).
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Created: 08/04/09 @ 19:25:05 | Last updated: 10/08/09 @ 12:06:18
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains the version of the KEGG pathway database used in the analysis of the Tir1 QTL region
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Created: 08/04/09 @ 19:23:53 | Last updated: 10/08/09 @ 12:08:00
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a list of KEGG gene identifiers, cross-referenced to UniProt and Entrez identifiers. The UniProt and Entrez ids were obtained from BioMart for genes located in the Tir1 QTL region.
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Created: 08/04/09 @ 18:06:23 | Last updated: 10/08/09 @ 12:10:07
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a list of KEGG gene descriptions, for each KEGG gene identified within the Tir1 QTL region.
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Created: 08/04/09 @ 18:00:35 | Last updated: 10/08/09 @ 12:12:09
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
The release of the Ensembl database used to identify genes in Tir1 QTL region.
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Created: 08/04/09 @ 17:57:57
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This spreadhseet contains all of the intersecting pathways between the Tir1 QTL and day 7 differentially expressed genes
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Created: 08/04/09 @ 17:56:10
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This spreadhseet contains all of the intersecting pathways between the Tir1 QTL and day 3 differentially expressed genes
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Created: 08/04/09 @ 17:53:46 | Last updated: 10/08/09 @ 12:30:59
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This spreadsheet contains information about the re-sequencing of the daxx gene, identified as a candidate QTg for the African Trypanosomiasis resiatance phenotype. This file is related to the paper: http://www.ncbi.nlm.nih.gov/pubmed/17709344
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Created: 08/04/09 @ 13:36:10 | Last updated: 10/08/09 @ 12:37:37
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This table contains a list of articles used to construct a list of issues with regards to the lack of systematic and explicit data analyses conducted in bioinformatcis. Each author list is linked directly to their publication within PubMed.
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Created: 08/04/09 @ 13:29:32
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains the results of re-sequencing the Daxx gene
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Created: 08/04/09 @ 13:27:20
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This protocol provides details on how to identify candidate genes from the returned workflow results.
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Created: 08/04/09 @ 13:23:03
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This PDF is my personal copy of the NAR publication.
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Created: 04/08/08 @ 17:49:10
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
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Created: 04/08/08 @ 17:40:21
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
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