Mining_the_Kegg_pathpath_to_input_file00 This takes the input of the local directory where the user has stored the GWAS output. It is necessary that the SNP IDs be present in the first column of the input file. 2012-08-29 17:42:29.660 UTC /home/marco/Dropbox/Wf4Ever/Reviews/year 2/Demo/UserMaterial/datasetmarkers_hgvrs487.txt 2013-01-23 09:50:52.729 UTC set_width00 100000 2012-08-29 17:52:38.326 UTC The allows the user to set the flanking width for the gene for determining SNPs 2012-08-29 17:51:43.227 UTC path_to_output_file00 /home/marco/Dropbox/Wf4Ever/Reviews/year 2/Demo/UserMaterial/output_snp_gene_pwy.txt 2013-01-23 09:51:17.553 UTC This takes the input of the local directory where the user has stored the GWAS output. It is necessary that the SNP IDs be present in the first column of the input file. 2013-01-22 13:27:57.785 UTC extract_snp_idstring0out100 This extracts the contents (snp_ids) of the first column from the input.It is important that the first column contains SNP IDs for this reason. 2012-08-29 17:47:52.146 UTC net.sf.taverna.t2.activitiesbeanshell-activity1.4net.sf.taverna.t2.activities.beanshell.BeanshellActivity string 0 text/plain java.lang.String true out1 0 0 workflow net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Parallelize 1 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.ErrorBouncenet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Failovernet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Retry 1.0 1000 5000 0 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.InvokeSplit_string_into_string_list_by_regular_expressionregex0string0split11 This service splits the string value into a string list at every occurrence of the specified regular expression. The regular expression provided in this case is a new line: "\n" 2012-08-29 17:45:33.119 UTC net.sf.taverna.t2.activitieslocalworker-activity1.4net.sf.taverna.t2.activities.localworker.LocalworkerActivity string 0 'text/plain' java.lang.String true regex 0 'text/plain' java.lang.String true split 1 l('text/plain') 1 workflow org.embl.ebi.escience.scuflworkers.java.SplitByRegex net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Parallelize 1 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.ErrorBouncenet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Failovernet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Retry 1.0 1000 5000 0 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Invokeregex_valuevalue00net.sf.taverna.t2.activitiesstringconstant-activity1.4net.sf.taverna.t2.activities.stringconstant.StringConstantActivity \n net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Parallelize 1 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.ErrorBouncenet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Failovernet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Retry 1.0 1000 5000 0 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Invokehsapiens_snphsapiens_snp.snp_filter_filter0hsapiens_snp.chrom_start10hsapiens_snp.chr_name10 This is a Biomart service that takes the SNP ID as the input and returns chromosome name, and the position of the SNP. 2012-08-29 17:49:44.511 UTC net.sf.taverna.t2.activitiesbiomart-activity1.4net.sf.taverna.t2.activities.biomart.BiomartActivitynet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Parallelize 1 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.ErrorBouncenet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Failovernet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Retry 1.0 1000 5000 0 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.InvokeFlatten_Listinputlist2outputlist11 This service flattens the inputlist by one level. It returns the result of the flattening. 2012-08-29 17:50:04.635 UTC net.sf.taverna.t2.activitieslocalworker-activity1.4net.sf.taverna.t2.activities.localworker.LocalworkerActivity inputlist 2 l(l('')) [B true outputlist 1 l('') 1 workflow org.embl.ebi.escience.scuflworkers.java.FlattenList net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Parallelize 1 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.ErrorBouncenet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Failovernet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Retry 1.0 1000 5000 0 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.InvokeFlatten_List_2inputlist2outputlist11 This service flattens the inputlist by one level. It returns the result of the flattening. 2012-08-29 17:49:59.830 UTC net.sf.taverna.t2.activitieslocalworker-activity1.4net.sf.taverna.t2.activities.localworker.LocalworkerActivity inputlist 2 l(l('')) [B true outputlist 1 l('') 1 workflow org.embl.ebi.escience.scuflworkers.java.FlattenList net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Parallelize 1 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.ErrorBouncenet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Failovernet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Retry 1.0 1000 5000 0 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Invokeinput_chr_positionchr_in1in21in11chr_out11end_out11start_out11 The purpose of this beanshell is to manipulate the start and end positions based on the flanking width provided by the user. 2012-08-29 17:54:24.874 UTC net.sf.taverna.t2.activitiesbeanshell-activity1.4net.sf.taverna.t2.activities.beanshell.BeanshellActivity chr_in 1 text/plain java.lang.String true in2 1 text/plain java.lang.String true in1 1 text/plain java.lang.String true chr_out 1 1 end_out 1 1 start_out 1 1 workflow net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Parallelize 1 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.ErrorBouncenet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Failovernet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Retry 1.0 1000 5000 0 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.InvokeRead_Text_Filefileurl0filecontents00 This service reads the text file at the specified file path or URL and returns the file's content. 2012-08-29 17:45:16.99 UTC net.sf.taverna.t2.activitieslocalworker-activity1.4net.sf.taverna.t2.activities.localworker.LocalworkerActivity fileurl 0 'text/plain' java.lang.String true encoding 0 'text/plain' java.lang.String true filecontents 0 0 workflow net.sourceforge.taverna.scuflworkers.io.TextFileReader UserNameHere 2011-12-02 20:12:09.377 UTC net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Parallelize 1 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.ErrorBouncenet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Failovernet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Retry 1.0 1000 5000 0 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.InvokeCreate_and_populate_temporary_file_2content0filepath00 This service creates a temporary file in a local tmp directory. 2012-08-29 18:10:19.8 UTC net.sf.taverna.t2.activitiesbeanshell-activity1.4net.sf.taverna.t2.activities.beanshell.BeanshellActivity content 0 'text/plain' java.lang.String true filepath 0 'text/plain' 0 workflow net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Parallelize 1 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.ErrorBouncenet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Failovernet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Retry 1.0 0 0 0 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.InvokeConcatenate_Files_2filelist1outputfile0 This service examines the files whose paths or URLs are specified in the filelist. The content of those files is concatenated. 2012-08-29 18:10:35.559 UTC net.sf.taverna.t2.activitieslocalworker-activity1.4net.sf.taverna.t2.activities.localworker.LocalworkerActivity filelist 1 l('text/plain') java.lang.String true outputfile 0 'text/plain' java.lang.String true displayresults 0 'text/plain' java.lang.String true results 0 'text/plain' 0 workflow net.sourceforge.taverna.scuflworkers.io.ConcatenateFileListWorker net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Parallelize 1 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.ErrorBouncenet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Failovernet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Retry 1.0 0 0 0 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.InvokeCheckFilenameinfilename0outfilename0outfilename00 This Beanshell prevents accidental overwrite of the input file by the output file. If filenames are equal it prepends "output_" to the output filename. 2013-01-23 17:45:10.61 UTC net.sf.taverna.t2.activitiesbeanshell-activity1.4net.sf.taverna.t2.activities.beanshell.BeanshellActivity infilename 0 text/plain java.lang.String true outfilename 0 text/plain java.lang.String true outfilename 0 0 workflow net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Parallelize 1 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.ErrorBouncenet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Failovernet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Retry 1.0 1000 5000 0 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.InvokeGene_to_PathwaySNP0chromosome0chrom_end0chrom_start0output_table11 This nested workflow extracts gene regulatory pathways from the KEGG database that are presumably affected by the SNPs identified by GWAS. 2013-01-30 07:55:04.209 UTC net.sf.taverna.t2.activitiesdataflow-activity1.4net.sf.taverna.t2.activities.dataflow.DataflowActivitynet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Parallelize 1 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.ErrorBouncenet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Failovernet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Retry 1.0 1000 5000 0 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.InvokeFlatten_List_3inputlist2outputlist11net.sf.taverna.t2.activitieslocalworker-activity1.4net.sf.taverna.t2.activities.localworker.LocalworkerActivity inputlist 2 l(l('')) [B true outputlist 1 l('') 1 workflow org.embl.ebi.escience.scuflworkers.java.FlattenList net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Parallelize 1 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.ErrorBouncenet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Failovernet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Retry 1.0 1000 5000 0 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Invokeextract_snp_idstringSplit_string_into_string_list_by_regular_expressionsplitSplit_string_into_string_list_by_regular_expressionregexregex_valuevalueSplit_string_into_string_list_by_regular_expressionstringRead_Text_Filefilecontentshsapiens_snphsapiens_snp.snp_filter_filterextract_snp_idout1Flatten_Listinputlisthsapiens_snphsapiens_snp.chr_nameFlatten_List_2inputlisthsapiens_snphsapiens_snp.chrom_startinput_chr_positionchr_inFlatten_Listoutputlistinput_chr_positionin2Flatten_List_2outputlistinput_chr_positionin1set_widthRead_Text_Filefileurlpath_to_input_fileCreate_and_populate_temporary_file_2contentFlatten_List_3outputlistConcatenate_Files_2filelistCreate_and_populate_temporary_file_2filepathConcatenate_Files_2outputfileCheckFilenameoutfilenameCheckFilenameinfilenamepath_to_input_fileCheckFilenameoutfilenamepath_to_output_fileGene_to_PathwaySNPSplit_string_into_string_list_by_regular_expressionsplitGene_to_Pathwaychromosomeinput_chr_positionchr_outGene_to_Pathwaychrom_endinput_chr_positionend_outGene_to_Pathwaychrom_startinput_chr_positionstart_outFlatten_List_3inputlistGene_to_Pathwayoutput_table 470b1948-bcb8-401e-88ee-72172c9a1c75 2012-05-25 14:15:48.972 UTC 59c48ad2-46fa-4c6a-920e-35585a726e7f 2012-07-13 12:50:51.21 UTC f0b2d523-78cc-49db-88a3-3c93c837b5fb 2012-05-29 09:17:34.988 UTC 909dac87-86fa-4b27-b8f0-e58b6acf0329 2011-12-02 20:03:51.11 UTC 396f1052-af35-4b0c-b81a-e6c80c9aa79b 2012-07-13 04:53:30.495 UTC 9d84acd8-2d53-46c1-b1d0-d395b26d5ffc 2012-05-25 14:14:15.364 UTC 50e39586-05d0-4cac-80e5-ca7476e4c62c 2012-05-28 13:06:09.328 UTC 6a975b77-984e-4396-92f0-74aaba68cc6e 2011-12-05 09:26:42.234 UTC 0e6e104f-a696-4555-9fd0-b8e6a84e960e 2012-08-29 17:56:05.884 UTC ea513290-65bf-47d1-a69e-347cac6a273f 2012-07-24 13:14:40.56 UTC 225e0718-30f5-4431-9c93-1367d0875f1c 2011-12-05 08:42:08.453 UTC 5a59c0b8-b1d0-4d7e-af85-b9c292bef2fa 2012-08-29 18:14:29.661 UTC 9dbddb98-bc13-49e4-99ea-abadf243ba48 2012-07-13 12:18:30.623 UTC 5a467702-34f4-41a2-8147-bed144e67082 2013-01-21 17:45:35.763 UTC 9e402cfc-fd28-4555-b7a0-75cb8851a823 2011-12-02 20:02:17.831 UTC df724031-6ef9-4bbf-80d1-0978f512f166 2012-05-24 07:13:09.787 UTC 4ed47709-f143-454e-9df8-fc1ee053577c 2012-05-28 14:45:04.634 UTC 7c853e04-989f-467d-960a-8ad72355c5f2 2012-05-29 09:56:07.94 UTC cdece6df-95ce-4f59-9f4d-c99dd46dad41 2013-01-21 19:13:45.867 UTC 9916b6e6-526d-4583-b390-64518c4f06a1 2012-07-13 03:37:35.435 UTC d2fab0b4-1886-49e3-b4e0-2ef4791554e3 2012-05-24 14:28:23.199 UTC 404b5061-dcee-4022-af0b-3f03ffb579d9 2012-07-10 13:47:51.897 UTC ba3d90fe-3286-4a20-9f70-1f96d3553cde 2012-05-25 14:43:53.153 UTC 18633aad-72f8-4de7-8355-7a3b41d2e782 2011-12-02 20:01:21.139 UTC 418d93b2-546c-4e33-b77a-9ef284b18392 2011-12-05 09:21:49.671 UTC 0d757f59-9497-426a-b0dd-bdb68d3796d0 2012-05-24 11:52:38.509 UTC 8ed5c836-7421-4937-82a4-afd071d36068 2012-05-28 15:49:27.444 UTC e9205450-f061-4220-a690-24780f575258 2012-05-24 10:09:38.171 UTC 661bc095-4dce-4ec9-885a-62cd4678a17d 2012-05-25 15:39:45.220 UTC 537f3d64-b1fd-43bd-9c13-ad4372dd7a51 2012-05-29 09:49:35.836 UTC 39ebc55b-a839-4ddb-854b-ff51dc377703 2012-05-28 14:11:19.840 UTC 7732d491-9163-41d3-b43e-07f5e3710a5b 2012-07-13 03:45:40.363 UTC 52aa7823-c531-4e64-9543-bbf57aa4c0de 2012-05-24 13:30:11.840 UTC bba91acb-8f29-45c8-b827-5fa8573f354d 2012-05-28 16:08:22.706 UTC d9d5b914-c845-47f6-baa5-4965149a3eb6 2012-05-28 13:14:24.783 UTC e2169816-71c1-4ae7-a75e-a6468bd44595 2013-01-23 17:47:33.987 UTC 3e653fd3-19df-4ad7-b46b-a47192bf6639 2012-07-13 03:09:16.430 UTC 21f88381-9624-4b53-b90d-338c89766640 2012-07-12 22:31:49.351 UTC d60af604-f923-4b3b-84a1-e5cab6eba64f 2012-05-24 10:23:12.911 UTC 388cc1a4-6e6d-4f55-b250-6783360f073d 2012-05-28 13:27:42.744 UTC f961460c-2aac-418a-82c8-c6f9bb84bc25 2012-05-23 09:33:23.569 UTC 011d4fd1-e2f8-4a95-aadb-1b9202ea3937 2013-01-22 01:28:08.792 UTC 136247cc-6e2d-4a2c-a703-590419195f99 2012-05-29 07:49:50.399 UTC d7cc4df4-9383-4543-870f-1beaa09c70f7 2012-05-29 10:05:40.594 UTC d32c5756-1d22-4b4a-9069-d37c43dc1b58 2013-01-21 17:58:20.660 UTC 0fe8a23c-ab84-4025-a5c0-27c652d9b7eb 2012-05-28 15:06:02.685 UTC 65969e5e-369b-46b3-88d7-22747d38898a 2012-05-29 09:14:34.991 UTC e33d1b5a-4387-40af-8eb3-610183d068a1 2012-05-25 14:48:46.775 UTC c79e9515-71ad-43a9-aaa5-b3c0b9f0c844 2012-05-23 09:32:11.351 UTC 880814c1-426f-4e59-8882-9241af442149 2012-05-28 15:50:25.224 UTC a3dc86e8-ceb9-4224-a702-83ef11cddaa1 2011-12-02 20:12:19.143 UTC b6009e1a-5bd6-44e3-bdd6-9af7c90bdc52 2012-05-25 14:17:37.221 UTC ec2bec87-7bbf-4e50-a8c6-86a2aac5435f 2012-05-28 15:30:15.216 UTC e8e28dad-160e-438f-b1a4-1bc0c952cee4 2012-05-29 08:10:33.77 UTC 68edacf2-b990-4a31-b694-c8cacd99e465 2011-12-02 20:18:54.225 UTC 4717b80f-c414-4cef-a833-5c7434445481 2011-12-04 20:17:49.522 UTC 773ad5ff-fa77-4807-9699-bc75f0be63b9 2011-12-04 19:55:52.32 UTC 0dd472cc-fca4-40c7-befc-dc40d070613e 2012-05-28 12:57:45.369 UTC aa8a665b-2e33-4b91-b596-c3b36cd8b714 2012-05-29 09:54:53.96 UTC 8fba433b-1a50-4c58-9d88-4ce23c30b3ab 2011-12-04 20:34:38.768 UTC f651a96e-f829-4d2c-812e-04b914799527 2012-05-24 14:16:55.168 UTC 1f9fa403-1de0-4605-ae95-7964bb2b2a91 2012-05-23 09:00:46.292 UTC 122b2bb9-fdc0-4545-a673-487ec8eb4c9f 2012-05-28 13:32:55.580 UTC 6b626d75-da3f-41fb-8446-76815e423e90 2013-01-22 21:35:48.581 UTC 3b8a830b-befd-4274-a627-de73d272b6f8 2011-12-05 10:11:10.661 UTC e70800df-db56-46cc-95c6-7331be9cfc22 2012-05-25 14:43:01.545 UTC c6a4b654-7519-49bf-bb26-82fd81e32d52 2012-05-28 14:47:56.177 UTC 08bfcf03-f582-482e-b95b-ae6f499143d0 2013-01-21 14:31:36.904 UTC 8369db6a-1d67-44e8-bdc0-5586d6ac2665 2012-07-09 14:27:40.403 UTC f4ba5bba-e195-456c-9fce-4c7a04ef8e23 2012-05-28 13:11:04.53 UTC 66d2a846-2d42-40a1-ac4a-0cb5ece59b2b 2012-07-13 19:44:04.313 UTC fbd6acb9-1f7a-485b-b210-72db3143c54d 2013-01-21 18:32:30.597 UTC c3eb4a90-1ef2-405e-8f56-e6f6ec2f87db 2012-05-28 15:46:04.713 UTC e30dc445-e2a0-43f3-bfd7-083d248b55da 2012-05-28 13:40:30.818 UTC 56d2388f-4512-4039-8ac5-376509658156 2012-07-10 16:26:23.285 UTC 6fe9cd02-1659-43c2-b2b5-5251f8b58c2d 2013-01-22 20:55:23.360 UTC aa106f23-15fa-4bde-8481-f38d9145ea4a 2012-05-28 15:24:47.801 UTC 2e5e5024-9bf2-4adf-befb-f4585fe28e0e 2012-05-24 10:11:45.87 UTC 5041e588-5b2c-46e2-bcd5-6df40c41b985 2012-07-13 10:56:58.41 UTC f8945a46-eff7-4297-a204-f80e05d0054d 2013-01-21 14:40:52.588 UTC 819a2da6-ac2f-450f-8898-ca47c9e17690 2012-05-28 13:26:14.402 UTC 6327f30f-f86f-407f-b65b-25dc8dd3a022 2012-05-28 15:28:42.515 UTC Mining the Kegg pathway database with the top hits from a GWAS, thereby predicting which gene regulatory pathways may be altered as a result of genetic mutations in a subpopulation. 2013-01-30 07:57:27.554 UTC f4bbc070-c3f5-48c7-bc3b-3e36572e755d 2012-05-28 15:21:02.683 UTC 31edde4d-c021-4050-8192-3547f650035e 2012-05-28 13:16:38.232 UTC 4e96a334-f577-4dbd-8ec0-d184aa0c403c 2013-01-23 04:14:48.784 UTC 1b31e1dc-c604-41cd-ada0-7a630d9ab202 2012-05-23 09:50:23.48 UTC 86fc5859-0361-485f-ac5e-efdac56e896c 2012-08-29 18:02:56.373 UTC 27f67a96-5a0f-4b9f-bc36-e487b3022324 2011-12-05 10:09:35.932 UTC 3e9f3842-9dfc-4b71-a356-a1516667a065 2012-05-28 16:29:16.964 UTC caeeda28-d63a-4967-86a1-60b9f82afdbc 2012-07-13 11:40:22.904 UTC 4a1ca2ff-c712-4787-bad3-b37c5f1531dd 2013-01-21 19:24:08.63 UTC 720aa582-de73-463d-b2bc-ddd1699ebc4b 2012-05-24 06:55:01.111 UTC 4002f6bd-d804-4219-bf5d-1e3da51e388d 2012-07-14 02:58:10.79 UTC 37852792-3988-4ca1-894b-f18c3e6caa3d 2012-05-28 13:36:48.449 UTC 9754d989-1173-40df-bed9-a561f2c102c5 2012-07-13 11:32:04.849 UTC e26cb189-f7ee-4b58-8a5a-383bbc50ade6 2013-01-22 00:57:40.770 UTC 131530e7-7bf2-440b-8ae4-7de74e470426 2012-05-28 14:56:56.476 UTC 7dfa4a0e-911a-49e7-8fa9-867599fe1acb 2012-05-28 14:13:25.228 UTC 98a34165-cf45-4fbb-92dd-9714728b200e 2012-05-28 15:34:06.993 UTC e489f882-ec1f-492a-b233-89afc3a5d998 2012-05-29 08:19:59.344 UTC 07448a4e-6711-403d-80a7-bbce3a10c9e5 2012-05-23 10:24:50.354 UTC 56f48acf-de19-4709-991f-cdc768c578d8 2012-07-09 14:15:50.905 UTC 906db120-9f44-4cfc-8b28-91468dfee79a 2013-01-22 01:55:17.932 UTC 20b3043a-15dc-4c96-a5aa-9fb1a5ade917 2011-12-05 13:10:38.566 UTC fcbc52b2-3f39-41cf-9eb2-f17badb0827c 2012-05-29 09:25:28.151 UTC 5579e4f5-3b8a-41b5-a0b9-5a73d4d8f8b8 2012-05-28 15:22:26.463 UTC 16fc0fde-d715-4380-8c10-4f4362d71ac8 2012-05-24 14:14:29.971 UTC 1e2fc50e-6f54-4c4b-854c-aecf80d24272 2012-05-23 09:11:52.877 UTC 79dc3865-dde2-4c84-88e4-3069af419363 2012-07-13 20:26:29.179 UTC b32a03e5-3a55-4c72-b3f5-5f041d859d25 2012-05-28 13:43:41.246 UTC 8b1ca805-f1a3-45c0-8dd0-c2367fb62494 2012-05-29 09:24:10.559 UTC ba6ce7ea-bec1-4cdc-8c9d-bae2d1086a9d 2012-05-24 10:04:37.281 UTC d80fb6b7-8bf4-47e1-8f44-2a03441e8566 2012-05-23 09:22:12.952 UTC 522e8f56-44cc-4dce-b9bc-55555eb4619e 2012-08-28 12:52:48.710 UTC 4a0bd72f-205f-4fe2-aabf-4811716d04a3 2012-05-28 15:35:32.913 UTC 12676d8e-8e07-44a8-adc3-246bed5f719e 2012-05-29 09:38:49.885 UTC 1daa084e-c7a2-45cd-addb-b2021c866f68 2013-01-23 04:45:41.767 UTC 92b50465-c47e-4f10-959f-6ac4ea412069 2012-07-13 10:53:40.120 UTC e5e29e4d-d497-493a-9860-a8bd8d565754 2012-05-24 07:11:13.72 UTC 0aaa6f86-7652-4191-91b9-933364dc640f 2012-05-28 13:39:00.742 UTC 33f3d4e3-80a9-44ec-8cfb-f84ebc21051c 2012-05-28 12:44:30.573 UTC 1db5c6f1-a905-41a5-83c8-d8f79cd16ffd 2012-05-28 14:17:31.656 UTC 86aae19c-517c-4f16-a964-4031ae65dcb2 2012-07-13 19:05:49.202 UTC f2dd9a4a-91c0-4c6a-aff4-43041ef6f4af 2012-05-24 10:07:59.36 UTC e2e11b86-8b2e-4567-8da8-f508470a7206 2012-05-24 10:05:09.857 UTC 489c0706-b993-44cc-878e-02cd52c0757a 2012-05-28 13:28:40.258 UTC 8b743d45-0ed3-40af-b86c-621a622becd7 2012-05-25 15:13:17.443 UTC 1a15a664-74ff-430c-8c5b-9a44b75c5d92 2012-05-24 10:24:32.110 UTC c98b52f2-07a9-41c1-93e2-537baaca690f 2012-05-25 14:45:00.606 UTC 663775b4-68ba-4dfe-8aa3-2a079a61805c 2012-05-28 13:17:48.527 UTC 0f479371-ee41-44bb-b265-76c85e659653 2012-05-24 11:30:53.380 UTC b83cbe30-8827-445a-91f6-e00ed0d12834 2013-01-21 14:20:32.12 UTC 63150755-7e2c-46fa-9b18-d0af094e6bdb 2012-07-13 11:16:52.800 UTC 892ce0b4-fffd-4962-a850-445e2afe54c9 2012-05-28 14:26:47.563 UTC 78bad41f-3d43-4052-9e7f-5619cb2866bc 2011-12-02 20:20:22.944 UTC 9ffd5551-67e7-42d9-b857-a449592ca31a 2012-07-13 11:48:52.784 UTC 9392534b-c27e-4185-9572-110f7d720aa3 2012-05-29 09:29:57.333 UTC 75a0e2b5-9b5d-469b-ad7b-c1714a700cea 2013-01-22 18:33:27.609 UTC 25b6de5f-396f-45c9-aaa2-e3277851f2c2 2011-12-05 09:29:51.46 UTC 27e830a9-637b-4bf3-bf0e-d612272830a7 2013-01-23 20:41:20.839 UTC 162f2322-5cc8-4872-992d-154c488ae2be 2012-07-13 11:06:07.271 UTC 9c66acfa-bc51-4c4a-aea4-52bbd719b3ee 2012-05-28 12:55:01.606 UTC 8dc439f6-ae2e-4484-9f61-d5913cbbc83e 2012-05-24 11:21:29.155 UTC 0550476f-da31-4066-b14f-f5f483f232fa 2012-05-28 13:12:01.864 UTC 9a5c4eb2-c8a0-4ab5-8733-2919f7a29c67 2011-12-04 20:23:12.582 UTC 9fa557e0-a81d-4bb4-9f0f-1cbdfe7cc68e 2012-07-13 03:11:34.351 UTC 65ab3f38-4108-4074-b641-0f8dc4770bc4 2013-01-22 00:46:17.855 UTC 1bb6dd60-a4c5-4e05-8e5e-84c9062b59fd 2013-01-22 18:35:41.359 UTC 4df0a34f-79f5-4db9-8139-c816c4e8dca4 2011-12-05 08:57:23.769 UTC 51b686d7-a903-449c-b10e-789e3eacaa77 2012-07-13 12:02:05.16 UTC b9ef661f-7b1e-4cd0-ad78-1f5f480c8f39 2013-01-21 18:36:43.8 UTC 63da0a3f-eb7a-4b96-a50f-476d09f0f6b8 2012-05-24 10:14:07.658 UTC 98b01cc5-cc3c-4a1b-b6bb-cc4e69c05340 2011-12-05 12:35:10.779 UTC c23caeac-180a-417b-b101-afa124068d22 2012-05-24 11:18:13.132 UTC c70559bc-32ea-45d5-9e0c-5c165efb1dce 2012-05-29 09:16:03.115 UTC 6d2380e8-5477-48e8-9ed1-c82d71a347fc 2012-05-24 11:32:30.203 UTC 365e4908-2036-409a-96c8-ce2adb53049d 2012-05-24 11:19:45.535 UTC 7984a5dc-f5ce-4991-aac7-0f4e76134197 2011-12-04 20:31:49.46 UTC baab0223-d7eb-45bd-b88a-add3ab069e7d 2013-01-22 23:23:16.308 UTC 8a7d22d5-e9ba-45b8-b0dd-017cb62649f3 2012-05-24 06:48:16.752 UTC 4f478714-44cb-4f1a-8f6f-93b7153386e5 2012-05-28 15:14:57.799 UTC eeaad7ea-4fbd-4283-b58f-68f1e9bb2a3c 2011-12-05 10:12:47.595 UTC 74431655-80e2-4cf3-b348-6b63f016e5f3 2012-07-13 19:10:56.745 UTC 49cf34cf-c5c0-4623-bf73-4a16d0750f9c 2012-07-12 23:18:21.867 UTC fe69338b-803c-4d67-9aaa-b8710bd72317 2011-12-05 09:02:50.152 UTC ea6091a1-78cb-41a5-932f-8123fa31fb24 2012-08-29 17:51:45.957 UTC 81319528-5815-4f1b-8b64-aa4532c0354b 2012-07-24 13:22:13.419 UTC 65737da5-8b7f-4f23-88ab-d2da3ad8cd9e 2012-07-09 14:26:27.567 UTC f070ba04-399b-4422-94e9-7ac859c74e0a 2012-05-28 14:48:31.535 UTC 7ffb408f-a8d9-4937-a761-0de05f695aee 2012-05-28 13:15:23.516 UTC 58640859-5834-45bc-8133-a44a208b0b22 2012-07-09 14:41:53.348 UTC c14f091a-a1b6-43a6-af28-7599b1ddd8b1 2012-05-24 07:08:23.312 UTC c43d0c46-4007-4474-a96e-17f9e6f94623 2011-12-05 12:39:09.738 UTC Genome-Wide Association studies (GWAS) with metabolomic phenotypes yield several statistically significant SNP-metabolite associations. To understand the biological basis of the association, scientists typically dwell on identifying genes in the vicinity of the SNP and the possible pathways that the gene participates in. The information needed to arrive at an understanding of the mechanistic basis of the association requires integration of disparate data sources. The purpose of this workflow is to take the GWAS output consisting of SNP-metabolite associations and return genes present in the vicinity of the SNP ( for example, ± 100 kb of the snp) and the pathways that these genes participate in. The user is provided with the choice of setting the flanking width to interrogate around the SNP. 2012-08-29 18:12:10.517 UTC 86c1c5b0-b948-4ef3-842e-ed08c6b9f6d9 2011-12-05 09:46:35.437 UTC d22656b0-2793-4ba7-8f90-1f80c27d5413 2012-07-10 12:46:34.516 UTC 1f39dd51-fbda-49c3-b718-aeb0ff17961f 2012-05-24 14:39:02.624 UTC a4414467-dc1d-49ce-9f35-ee643b2b0a92 2012-05-24 07:40:13.121 UTC 42a8db21-13e9-427a-9ed4-3ec73e5d09ad 2012-05-24 10:18:21.504 UTC 139030fb-d44e-450a-904b-57eb97587c55 2013-01-29 23:10:21.513 UTC c65a9a3a-909c-42a3-83cf-edd32d2e7aa9 2012-05-23 09:39:51.321 UTC cf450f3d-440a-44fe-8f3e-8f512e410dea 2013-01-21 17:49:53.754 UTC 761dc8af-f42e-47b0-a69b-b68ee156be89 2012-05-24 11:35:02.275 UTC de94784e-ff3b-455a-b46d-115a3425f870 2012-07-12 22:58:00.866 UTC d5acc483-c168-468a-b09f-aa0e5bdd691e 2012-05-23 09:20:31.391 UTC 01b0a1c2-2ea1-42fb-8f77-3102cb2029c3 2012-05-24 08:02:12.628 UTC 799b2c7a-749d-4e85-96b8-57d4ce9d49a8 2012-05-28 13:49:09.988 UTC 5b0b16b2-6159-4a45-8f0e-e61e52a42ed0 2011-12-05 12:50:24.222 UTC 7b6b6168-7421-4b1a-93e6-b6903bf56c49 2012-07-13 04:55:09.867 UTC 6dc63288-570b-4c6f-9d1b-3018852941bf 2012-05-24 14:32:15.752 UTC c5edb75b-4a94-4aa8-80a7-05d514432719 2011-12-05 12:41:04.327 UTC 82caace9-db1a-4b08-8528-7fed9f4fe3e3 2012-07-13 02:54:14.662 UTC 594f53e9-a4fd-422b-b11a-c95aeae12f6b 2012-05-25 14:18:14.345 UTC e2cf19ae-7516-4842-9c8d-7243da52e6fd 2012-05-28 13:23:25.66 UTC 1f56ace0-7a91-4cdb-80d2-078c96175c7a 2012-05-24 07:59:59.475 UTC 47ef6c53-e808-453a-9b0d-24d677a14b29 2013-01-21 19:06:21.233 UTC 07f68d25-cfa2-431a-a66f-7f30ffbef86c 2012-05-29 07:46:27.651 UTC f3fd6d4a-3b5a-4b82-a980-54ffd3b55e7b 2012-05-28 14:23:40.396 UTC 72797bde-afec-453a-831c-bc752526ec9b 2012-07-12 22:54:04.805 UTC 8c224453-74af-4dc1-b033-04077f1fb511 2013-01-22 01:41:10.640 UTC b31c16f3-c7f3-4f45-8808-dbcca2286761 2012-05-28 13:50:16.908 UTC fc7d0b18-95da-435a-a49c-bd4957d01929 2012-05-28 13:22:58.144 UTC 56ab1507-d44d-4569-b627-7984fe3da0aa 2011-12-05 08:55:56.457 UTC 343ea31a-d25d-40e2-9d94-bb1063033339 2011-12-04 21:31:09.853 UTC 09ff0ed8-017f-41e2-a5ac-8b25a86d1896 2012-05-24 07:14:01.348 UTC 8c5e8e26-1959-47e8-931a-f3d605354524 2011-12-04 20:25:27.361 UTC 2ff5f42c-ad5d-4855-afb6-994d95b56ad5 2011-12-05 12:45:17.858 UTC 9052cca1-3bac-456e-8964-bc5a97f24e12 2012-05-23 09:47:46.18 UTC a8101120-66aa-437d-9f54-7c75e8bcb4c6 2012-05-29 09:41:06.977 UTC 815b4de2-2533-4c65-acc1-61570ff0b7db 2012-05-28 14:46:29.632 UTC 44ce7b0d-aacc-4d8b-a074-befeb5e37ad5 2012-05-28 13:44:39.89 UTC 7e4d6ec1-007e-41b3-9b1a-39923c3843b6 2012-05-23 08:54:08.937 UTC ec0e7612-1c64-4ad5-8679-1acb05a4402d 2013-01-21 18:38:57.231 UTC 04515fdf-982c-4719-be61-f40e956f141c 2013-01-22 21:27:40.925 UTC 323b72ad-2dad-491c-adcc-4b01f61d15c5 2012-07-13 03:48:12.471 UTC e7471436-942d-4d3e-98b2-65e15995183e 2012-05-28 16:15:51.854 UTC 4c1c8924-c2c3-4410-bf73-5db2e4435998 2012-07-09 14:51:20.747 UTC e2de6396-8637-4edd-97cf-dd67d9c9a188 2013-01-21 18:31:06.282 UTC 934a7783-3866-49c3-be45-9f6c00f25f04 2012-05-28 13:42:43.45 UTC 4c18297b-d76f-494c-8e02-db4f29a0bb0d 2012-05-29 07:52:34.240 UTC c56efe86-559d-4878-be09-c8fe762aa032 2013-01-22 01:13:40.650 UTC fe2b3810-d054-405f-8693-866dde2fcc60 2012-05-24 10:26:45.775 UTC 2ce8d6ce-78ef-4ba3-93f3-ae418cb04a04 2012-05-24 11:37:44.705 UTC 3d9a2e4e-9eaf-46ef-ac71-9ba04a52c4ba 2011-12-04 20:51:57.350 UTC 681bb15e-0cb0-4d46-b94d-50c8af23d582 2011-12-05 10:05:00.123 UTC b997e938-3b2d-4ac3-a0ec-b90fa5ecfb86 2012-05-24 07:56:27.406 UTC 93602cc4-585d-434c-99f1-de25ffa08771 2012-07-12 23:08:39.267 UTC 0451f80c-fe7f-49b1-bb8c-9c26794e810e 2013-01-22 00:31:43.152 UTC 45f3551e-d015-4ca6-b0df-e1607fa965b0 2012-05-28 14:22:00.164 UTC c412f440-ef73-4927-9219-fa5c5c2ab2b1 2013-01-29 22:34:03.278 UTC 67bf7e76-47ea-4757-9d02-de763fba160b 2012-07-13 11:25:00.588 UTC 354bd383-3970-46e5-a69d-756f249db3fd 2011-12-02 20:06:00.39 UTC e421f76c-a367-48df-bd76-f1e283b3c15a 2013-01-29 23:32:41.522 UTC f6370d45-5817-4828-98e5-8fa459e52876 2012-05-28 13:30:49.145 UTC bb845add-ef95-4621-ba20-7cdbcfd8895c 2012-05-28 14:30:06.480 UTC 9d9f8d6e-d1d7-4eed-957b-06cfbda544bf 2013-01-29 22:36:49.631 UTC 8481be24-7358-4c81-a8fc-2b2b89f0069e 2012-07-14 03:17:33.803 UTC 16ea68c5-c95d-4d0e-b08e-ea5c296e1ab3 2012-05-24 07:16:16.281 UTC 2df74fd6-bad1-407a-96ed-5d789a5d790d 2012-07-12 22:38:14.266 UTC bd87bc54-b86c-48c1-9bcc-0d943cad671e 2011-12-02 19:52:46.244 UTC 225c56b9-df03-416e-bfef-ba2eb57a22cc 2012-05-24 11:45:35.231 UTC a26f21c0-c5db-44b1-827c-d5f5533fb71a 2013-01-21 19:36:00.520 UTC 92446b4f-a77a-40b3-ac48-d594e65ca32a 2012-08-28 12:45:58.86 UTC c0b817e8-664b-4f21-8737-6cdde6c33e72 2012-07-13 20:13:19.177 UTC dac0d18e-8eed-41d5-82c9-fea7dda921cc 2013-01-23 04:46:30.659 UTC 2f2cdb4e-8d9a-4fae-826b-09049e317d3e 2012-07-24 12:10:49.441 UTC a9221629-d5b6-460f-89db-3cb48f9f6034 2012-08-29 17:57:55.615 UTC d7b84de5-d36a-4090-8ab4-d37dde019b32 2012-05-28 14:18:44.466 UTC 08489858-3622-42b4-8645-a7508a5a7eea 2012-05-24 11:49:05.799 UTC bccb19ff-4ec7-48a0-ac70-c04c1b1c0ad1 2012-05-24 10:21:12.433 UTC d842447e-78c3-4840-8f6b-b4425354f232 2013-01-29 22:53:37.193 UTC 9df76bf6-9c7e-47b3-bb5a-aadbcde0902c 2012-05-29 10:01:12.633 UTC 3105f50e-deab-4464-8ac2-ab81746a8e1a 2012-05-28 15:01:00.409 UTC 46cc1de8-0520-4575-b89c-e976f24a0209 2013-01-30 07:57:31.907 UTC a8e9dc49-d486-4d55-a5a2-8de2e51149ea 2012-05-24 10:16:40.525 UTC 16c48a91-f694-48c0-9554-2e4694e04c61 2012-05-24 14:42:37.630 UTC 6f449fd4-dbf2-46c2-80e4-b748c6b93354 2012-08-29 18:06:42.230 UTC b8ca8ea8-4261-47cf-826e-005f5d965883 2012-05-24 11:42:23.255 UTC f894d03f-e142-475a-91e5-d97606dde276 2012-05-23 09:13:55.875 UTC b594a08d-11fc-459b-9243-491bd5c0feda 2012-07-13 03:03:20.745 UTC 509480d2-5e56-46b9-a210-e1abd7f4fd59 2011-12-05 09:36:01.703 UTC d53f5b51-874e-4b1e-809f-b66e9663cf8f 2012-05-28 15:41:56.31 UTC cdf314f3-c07d-4299-9f12-b2fb34f16d71 2011-12-05 10:24:34.417 UTC 78067d1f-1fb1-404d-9494-50154802f9d9 2012-07-09 14:24:55.244 UTC 3173b7fc-97e4-43c3-9494-e09ca7ab0009 2012-07-13 20:07:19.961 UTC 57237b54-36f7-4a2c-9833-4ab73bf3cea9 2011-12-02 20:06:32.660 UTC 7aa641e8-23f2-447d-a8df-3310d951ac7b 2013-01-22 02:32:51.138 UTC a8ff4a9e-1161-41d9-b903-4d1fd1fd25e4 2012-05-29 09:13:08.665 UTC 8a72c4e8-34e8-4850-99d8-7edfef99eb59 2012-07-10 16:28:46.151 UTC 3dda2869-f2ca-4f37-a425-f527242e1816 2013-01-22 13:28:42.555 UTC 6ee5dac9-47db-4acf-8de3-4baf71ac2e0e 2012-05-24 07:12:27.913 UTC eedbb948-296f-448a-baec-81e9fe57a61f 2012-05-24 06:58:44.89 UTC 780ac0b7-a424-49aa-9a7f-deb714fb52a6 2012-05-28 13:48:07.271 UTC 43260d53-f13f-4b02-8755-96eb198c7a13 2012-05-28 13:42:07.264 UTC 2082c444-8dc5-491d-98f0-a38e48f14ad2 2012-05-28 14:58:09.975 UTC d7ddba62-2e21-4c6d-aaba-6bd5600af8b0 2012-05-29 09:45:01.263 UTC 442fbd70-6edc-4aac-a52a-1e28af391883 2011-12-02 20:21:29.89 UTC 1a646255-725f-4301-a6bf-36c1ac11b77e 2013-01-22 01:04:50.414 UTC c5bd0205-5369-43d1-99b8-97d96b84f515 2012-05-24 10:25:41.575 UTC bfd2dad7-f2a2-444c-b41c-cd7e7b1419b6 2012-08-29 17:44:03.978 UTC aa1e05f9-bef7-4a1e-9137-f9a139fc6328 2012-05-28 16:17:11.384 UTC ad7a20f3-6db0-433c-a89b-7bc51981d440 2013-01-23 09:51:26.181 UTC 3b268f07-e232-491d-874d-fdcb50b1210f 2012-05-24 06:49:32.736 UTC 4e8abbc2-c7d4-4763-a86a-b9238bc71a0a 2012-05-23 09:46:24.941 UTC c6954af8-29d3-49f2-9034-38847f1dd890 2012-05-28 14:28:31.311 UTC 821e379f-0aaf-4220-8d6c-83517950317f 2012-05-25 15:10:34.774 UTC 5feed474-e086-436c-9dc8-547e6f6648bc 2012-05-25 14:20:34.984 UTC 06ea5d6f-5cb6-4da7-8c34-66c9a16da0f6 2013-01-22 21:13:24.462 UTC de5376be-26df-4424-82f6-735797ecbb4d 2011-12-04 19:54:39.289 UTC f02a8cf2-7757-4252-b5ac-ad6729f9d80f 2011-12-05 08:51:49.367 UTC Harish Dharuri 2012-08-28 12:32:45.891 UTC 87ea0a35-0f9e-4fdb-bf4f-29dafeab759e 2011-12-05 09:20:36.359 UTC 55699458-d13b-44c4-88a3-00b9a94d4bfd 2011-12-04 20:29:57.352 UTC 689a09b4-747d-4616-8bea-f7d4c9cfad1d 2012-05-29 08:00:06.553 UTC b24b56c6-07da-42d1-b0ad-6560093cf6b7 2013-01-22 18:07:21.976 UTC 400ed11a-24fd-457a-a9b7-cc3ef85e8ad7 2012-05-24 11:44:12.16 UTC 6cba3d8f-b595-4757-8de7-d6c413032b29 2012-05-29 09:57:51.420 UTC 68b6a3a4-b582-4e29-9b7f-29c44c5c265b 2012-05-28 13:32:12.424 UTC 178f4858-1d1d-4749-993b-5c50c35fce9e 2012-05-29 09:34:11.328 UTC 04371b1b-18bd-4405-a82d-c3db639977a0 2011-12-04 20:35:38.750 UTC 73ef94bb-6b99-402a-9305-e57e5ce4f5dc 2012-07-13 10:41:55.216 UTC e1852394-62d4-4ebf-b574-803b0a8e9276 2012-05-24 06:52:22.865 UTC 8a9d0600-5882-4aae-949d-9eb085ad7781 2012-08-29 18:10:37.197 UTC fef62021-666b-465c-8cf1-352a75ae68ab 2013-01-22 00:50:17.378 UTC Gene_to_PathwaySNP00chromosome00chrom_start00chrom_end00output_tableConvert_to_Kegg_idstring0out100net.sf.taverna.t2.activitiesbeanshell-activity1.4net.sf.taverna.t2.activities.beanshell.BeanshellActivity string 0 text/plain java.lang.String true out1 0 0 workflow net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Parallelize 1 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.ErrorBouncenet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Failovernet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Retry 1.0 1000 5000 0 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.InvokeFlatten_List_6inputlist2outputlist11net.sf.taverna.t2.activitieslocalworker-activity1.4net.sf.taverna.t2.activities.localworker.LocalworkerActivity inputlist 2 l(l('')) [B true outputlist 1 l('') 1 workflow org.embl.ebi.escience.scuflworkers.java.FlattenList net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Parallelize 1 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.ErrorBouncenet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Failovernet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Retry 1.0 1000 5000 0 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.InvokeFlatten_List_3inputlist2outputlist11net.sf.taverna.t2.activitieslocalworker-activity1.4net.sf.taverna.t2.activities.localworker.LocalworkerActivity inputlist 2 l(l('')) [B true outputlist 1 l('') 1 workflow org.embl.ebi.escience.scuflworkers.java.FlattenList net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Parallelize 1 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.ErrorBouncenet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Failovernet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Retry 1.0 1000 5000 0 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Invokeget_compoundquery0responseBody00net.sf.taverna.t2.activitiesrest-activity1.4net.sf.taverna.t2.activities.rest.RESTActivity GET http://rest.kegg.jp/get/{query} text/xml application/xml String false false false false true query java.lang.String net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Parallelize 1 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.ErrorBouncenet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Failovernet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Retry 1.0 1000 5000 0 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Invokeextract_pathway_from_compounds_filein10out111net.sf.taverna.t2.activitiesbeanshell-activity1.4net.sf.taverna.t2.activities.beanshell.BeanshellActivity in1 0 text/plain java.lang.String true out1 1 1 out2 1 1 workflow net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Parallelize 1 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.ErrorBouncenet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Failovernet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Retry 1.0 1000 5000 0 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Invokealign_snp_gene_pwyin21in10out111net.sf.taverna.t2.activitiesbeanshell-activity1.4net.sf.taverna.t2.activities.beanshell.BeanshellActivity in1 0 text/plain java.lang.String true in2 1 text/plain java.lang.String true out1 1 1 workflow net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Parallelize 1 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.ErrorBouncenet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Failovernet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Retry 1.0 1000 5000 0 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.InvokeFlatten_List_7inputlist2outputlist11net.sf.taverna.t2.activitieslocalworker-activity1.4net.sf.taverna.t2.activities.localworker.LocalworkerActivity inputlist 2 l(l('')) [B true outputlist 1 l('') 1 workflow org.embl.ebi.escience.scuflworkers.java.FlattenList net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Parallelize 1 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.ErrorBouncenet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Failovernet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Retry 1.0 1000 5000 0 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Invokealign_snp_gene_and_extract_gene_idin10in21in31out111 This beanshell aligns the input snp ids with the corresponding genes present in the vicinity. 2012-08-29 17:57:01.249 UTC net.sf.taverna.t2.activitiesbeanshell-activity1.4net.sf.taverna.t2.activities.beanshell.BeanshellActivity in1 0 text/plain java.lang.String true in2 1 text/plain java.lang.String true in3 1 text/plain java.lang.String true out1 1 1 workflow net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Parallelize 1 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.ErrorBouncenet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Failovernet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Retry 1.0 1000 5000 0 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Invokehsapiens_gene_ensemblhsapiens_gene_ensembl.chromosome_name_filter0hsapiens_gene_ensembl.start_filter0hsapiens_gene_ensembl.end_filter0hsapiens_gene_ensembl.entrezgene10hsapiens_gene_ensembl.hgnc_symbol10 This is a Biomart service that takes the chromosome name and start and end positions and returns genes (entrez gene id) present in the region. 2012-08-29 17:56:03.919 UTC net.sf.taverna.t2.activitiesbiomart-activity1.4net.sf.taverna.t2.activities.biomart.BiomartActivitynet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Parallelize 1 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.ErrorBouncenet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Failovernet.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.Retry 1.0 1000 5000 0 net.sf.taverna.t2.coreworkflowmodel-impl1.4net.sf.taverna.t2.workflowmodel.processor.dispatch.layers.InvokeConvert_to_Kegg_idstringalign_snp_gene_and_extract_gene_idout1Flatten_List_6inputlistalign_snp_gene_and_extract_gene_idout1Flatten_List_3inputlistConvert_to_Kegg_idout1get_compoundqueryFlatten_List_3outputlistextract_pathway_from_compounds_filein1get_compoundresponseBodyalign_snp_gene_pwyin2extract_pathway_from_compounds_fileout1align_snp_gene_pwyin1Flatten_List_6outputlistFlatten_List_7inputlistalign_snp_gene_pwyout1align_snp_gene_and_extract_gene_idin1SNPalign_snp_gene_and_extract_gene_idin2hsapiens_gene_ensemblhsapiens_gene_ensembl.entrezgenealign_snp_gene_and_extract_gene_idin3hsapiens_gene_ensemblhsapiens_gene_ensembl.hgnc_symbolhsapiens_gene_ensemblhsapiens_gene_ensembl.chromosome_name_filterchromosomehsapiens_gene_ensemblhsapiens_gene_ensembl.start_filterchrom_starthsapiens_gene_ensemblhsapiens_gene_ensembl.end_filterchrom_endoutput_tableFlatten_List_7outputlist Purpose: Get KEGG pathways for the genes within a region around the SNPs that were derived from a GWAS, using a BioMart service. 2013-01-29 21:59:23.198 UTC 95bafc45-26db-481b-b684-1faa81095322 2013-01-29 22:20:05.107 UTC Marco Roos 2013-01-29 21:57:56.844 UTC Gene to Pathway 2013-01-29 21:58:05.707 UTC abd08f5d-deef-47a4-9212-66028ecb040e 2013-01-29 21:59:43.663 UTC aec28eb5-0d90-4601-9104-128d03e39b07 2013-01-29 22:07:16.961 UTC