Sacs Gene Muation Analysis

Created: 2010-11-03 17:23:21      Last updated: 2010-11-03 17:23:22

This workflow was created to predict the effect of the mutation on the primary and the secondary structure of a mutated sacsin protein.

The genomic sequence bearing the mutation should be pasted on FASTA format as input for the Transeq tool. This sequence will be translated to protein and compared to the wild type protein, already extracted from NCBI database, through the Supermatcher tool. Variation(s) will be verified by multiple alignment using Blastp and ClustalW tools.

Prediction of the variation(s) effects will be proceeded by four online tools : Pepstat, Garnier, hmoment and Pepinfo tools. All the results can be extracted from the workflow general report by clicking on "provenance".

This workflow can be used for other mutation analysis in other genes or proteins by modifying the accession number on the "execute query" step of the workflow.

Information Preview

Medium

Information Run

There was a problem when determining the run options of this workflow.


Information Workflow Components

Not available

Information Workflow Type

BioExtract Server

Information Uploader

Information License

All versions of this Workflow are licensed under:

Information Version 1 (of 1)

Information Credits (1)

(People/Groups)

Information Attributions (0)

(Workflows/Files)

None

Information Tags (0)

None

Log in to add Tags

Information Shared with Groups (1)

Information Featured In Packs (0)

None

Log in to add to one of your Packs

Information Attributed By (0)

(Workflows/Files)

None

Information Favourited By (0)

No one

Information Statistics

 

Citations (0)

None


Version History

In chronological order:



Reviews Reviews (0)

No reviews yet

Be the first to review!



Comments Comments (0)

No comments yet

Log in to make a comment




Workflow Other workflows that use similar services (0)

There are no workflows in myExperiment that use similar services to this Workflow.