Workflow Entry: Lymphoma type prediction based on microarray data

Created at: 11/05/10 @ 19:04:30      Last updated: 11/05/10 @ 19:04:32
Information Version 7 (latest) (of 7)
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Version created on: 11/05/10 @ 19:04:30 by: Wei Tan   |   Revision comments Expand

Title: Lymphoma type prediction based on microarray data

Type: Taverna 2


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Scientific value Using gene-expression patterns associated with DLBCL and FL to predict the lymphoma type of an unknown sample. Using SVM (Support Vector Machine) to classify data, and predicting the tumor types of unknown examples. Steps Querying training data from experiments stored in caArray. Preprocessing, or normalize the microarray data. Adding training and testing data into SVM service to get classification result.


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Processors (3)
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Taverna 2

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Citations (3)

1. Wei Tan, Ravi Madduri, Alexandra Nenadic, Stian Soiland-Reyes, Dinanath Sulakhe, Ian Foster, Carole A. Goble, caGrid Workflow Toolkit: A Taverna based workflow tool for cancer Grid, BMC Bioinformatics, 02 November 2010, http://www.biomedcentral.com/1471-2105/11/542, Accessed at: 03 September 2011

2. caArray, Experiment data: Diffuse large B-cell lymphoma outcome prediction , 23 April 2009, https://array.nci.nih.gov/caarray/project/golub-00095, Accessed at: 23 April 2009

3. MA Shipp et al, Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning, NATURE MEDICINE, 23 January 2002, http://www.broad.mit.edu/mpr/publications/projects/Lymphoma/Shipp_et_al_2002.pdf, Accessed at: 23 April 2009


Version History

Earliest Version:
[1] - Lymphoma type prediction based on microarray data

Created on: Thursday 23 April 2009 @ 17:10:37 (GMT)

Created by: Wei Tan

Last edited on: Thursday 23 April 2009 @ 17:15:00 (GMT)

Last edited by: Wei Tan

Revision comments:

None

Previous Versions:
[2] - Lymphoma type prediction based on microarray data

Created on: Friday 15 May 2009 @ 18:13:17 (GMT)

Created by: Wei Tan

Revision comments:

We added another classification service, KNN into the previous version.

[3] - Lymphoma type prediction based on microarray data

Created on: Tuesday 09 June 2009 @ 22:10:13 (GMT)

Created by: Wei Tan

Revision comments:

The workflow is now organized into three nested workflows.

With more explanations and instructions on input.

 

Output is more readible as a CSV string.

[4] - Lymphoma type prediction based on microarray data

Created on: Tuesday 28 July 2009 @ 17:17:03 (GMT)

Created by: Wei Tan

Revision comments:

Added the version presented at caBIG annual meeting 09.

[5] - Lymphoma type prediction based on microarray data

Created on: Monday 16 November 2009 @ 06:16:23 (GMT)

Created by: Wei Tan

Revision comments:

updated with the upgrade of caArray service v 2.3.

[6] - Lymphoma type prediction based on microarray data

Created on: Monday 16 November 2009 @ 06:21:17 (GMT)

Created by: Wei Tan

Revision comments:

update the workflow to work with caArray 2.3

Latest Version:
[7] - Lymphoma type prediction based on microarray data

Created on: Tuesday 11 May 2010 @ 19:04:30 (GMT)

Created by: Wei Tan

Revision comments:

the genepattern grid services moved to broadinstitute.org



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Workflow Other workflows that use similar services (4)

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Original Uploader

Workflow caArray data retrieving (v1)

Created: 23/11/09 @ 18:09:47

Credits: User Wei Tan

License: Creative Commons Attribution-Share Alike 3.0 Unported License

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Query all the gene expression data in a caArray experiment. Returns a evenly divided gene expression data set with corresponding class information. They ca be later used as training and test data set in many classification algorithms.Query all the gene expression data in a caArray experiment. Returns a evenly divided gene expression data set with corresponding class information. They can be later used as training and test data set in many classification algorithms.

Rating: 0.0 / 5 (0 ratings) | Versions: 1 | Reviews: 0 | Comments: 3 | Citations: 0

Viewed: 48 times | Downloaded: 19 times

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Original Uploader

Workflow genePattern data preprocessing (v2)

Created: 24/05/10 @ 22:42:38 | Last updated: 24/05/10 @ 22:42:39

Credits: User Wei Tan

License: Creative Commons Attribution-Share Alike 3.0 Unported License

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preprocess data set using genePattern preProces service, the input should be in genePattern STATML format. Configuration parameters can be adjusted by changing the default preprocess data set using genePattern preProces service, the input should be in genePattern STATML format.preprocess data set using genePattern preProces service, the input should be in genePattern STATML format. Configuration parameters can be adjusted by changing the string constants.

Rating: 0.0 / 5 (0 ratings) | Versions: 2 | Reviews: 0 | Comments: 0 | Citations: 0

Viewed: 59 times | Downloaded: 31 times

Tags (5):

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