File Entry: Parameter Estimation for Simulation of Glycolysis Pathway by Using an Improved Differential Evolution

Created: 2012-05-11 02:28:43      Last updated: 2012-05-11 02:28:44
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Version created on: 2012-05-11 02:28:43


Information Description

 An improved differential evolution (DE) algorithm is proposed in

this paper to optimize its performance in estimating the germane parameters for
metabolic pathway data which is used to simulate glycolysis pathway for
Satcharomyces cerevisiae. This study presents an improved algorithm of
parameter sensitivity test into the process of DE algorithm. The result of the
improved algorithm is testified to be better than the other estimation algorithms.
The outcomes from this study promote estimating of optimal kinetic
parameters, shorter computation time and ameliorating the precision of the
simulated kinetic model for experimental data.

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