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Blob Especiación del fósforo en sedimentos de un río trop...

Created: 2016-08-01 00:45:56

Credits: User William Senior

License: Creative Commons Attribution-Share Alike 3.0 Unported License

En este estudio, se empleó una modificación del método de extracciónsedimentaria (SEDEX) para cuantificar las diferentes formas de P en lossedimentos recolectados en río Cuchivero durante marzo del año 2014. El rango devariación de las concentraciones de las diferentes formas de P respecto al P total(PTf) fueron 4,84-7,49 gP/g para la fracción F1 constituida por el Pintercambiable (P-ad) más el asociado a óxidos de hierro (...

File type: Adobe PDF

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Workflow TRPV1 Bioactivity from ChEMBLdb13 and ChEM... (1)

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This workflow allows to extract bioactivity data stored in ChEMBLdb for human TRPV1. Ensure you have installed Chembl and RDKit extensions to run the workflow.

Created: 2016-07-27 | Last updated: 2016-07-27

Credits: User Daria Goldmann

Workflow KNIME workflow without hERG labels include... (1)

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KNIME workflow used to retrieve and process data from Open PHACTS for three targets of interest (hSERT, hDAT, hERG). Further, Murcko scaffolds are computed and selectivity trends towards hSERT and hDAT can be studied. Cutt off's for separating actives/inactives are tailored to the specific target and endpoint.Requirements:- Knime v2.11- Open PHACTS Knime nodes version 1.1.0: https://github.com/openphacts/OPS-Knime- KNIME additional community nodes: 'Trusted Community Contributions (2....

Created: 2016-07-20 | Last updated: 2016-07-20

Credits: User Barbara Zdrazil Network-member Open PHACTS

Workflow KNIME workflow with hERG labels included f... (1)

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KNIME workflow used to retrieve and process data from Open PHACTS for three targets of interest (hSERT, hDAT, hERG). Further, Murcko scaffolds are computed and selectivity trends towards hSERT and hDAT can be studied. Compounds/scaffold series are flagged by their ability to also inhibit hERG.Requirements:- Knime v2.11- Open PHACTS Knime nodes version 1.1.0: https://github.com/openphacts/OPS-Knime- KNIME additional community nodes: 'Trusted Community Contributions (2.11)': EMBL-EBI No...

Created: 2016-07-20 | Last updated: 2016-07-20

Credits: Network-member Open PHACTS

Creator

Pack KNIME workflows from Zdrazil et al, MedChemComm, 201...


Created: 2016-07-20 06:21:03 | Last updated: 2017-06-22 13:35:07

Included are 2 KNIME workflows for data retrieval and processing:1) a KNIME workflow called "Transporter_Profiling_SERT_DAT_HERGlabel" with HERG labels included2) a KNIME workflow called "Transporter_Profiling_SERT_DAT_Ki_IC50_tailored_TH" without HERG labels

7 items in this pack

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Workflow An example BRAIN api call (1)

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An example brain API call.Note: This workflow require RServe library. Please refer to this link for the instructions to install RServer    

Created: 2016-07-11 | Last updated: 2016-07-11

Credits: User Rajireturn

Creator

Pack Telehealth Initiatives to Improve Efficiency and Qua...


Created: 2016-07-06 08:21:38

Over the past two decades, plenty of telehealth applications have been successfully implemented. Applications such as the transfer of digital photos and patient records and the use of medical video endoscopes to monitor patients’ physical examination have demonstrated great results. For many players, the introduction of telehealth in the global medical tourism market has been a profitable strategy.Telehealth improves the efficiency, customer service, and quality of medical tourism servi...

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Uploader

Blob Zinc deficiency induces apoptosis via mitochondrial ...

Created: 2016-06-29 08:02:03

Credits: User Edwin Levinson

License: Creative Commons Attribution-Share Alike 3.0 Unported License

Previous studies have shown that zinc deficiency leads to apoptosis of neuronal precursor cells in vivo and in vitro. In addition to the role of p53 as a nuclear transcription factor in zinc deficient cultured human neuronal precursors (NT-2), we have now identified the translocation of phosphorylated p53 to the mitochondria and p53-dependent increases in the pro-apoptotic mitochondrial protein BAX leading to a loss of mitochondrial membrane potential as demonstrated by a 25% decrease in JC-1...

File type: Adobe PDF

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Workflow KEGG:Get PW for met (1)

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The purpose of the workflow is to retrieve all the pathways that the input metabolite(s) participates in.

Created: 2016-06-21

Credits: User Kristina Hettne User Harish Dharuri

Attributions: Workflow KEGG:Pathway Scheme

Workflow chebi2keggID (1)

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This workflow converts a (list of) chebi identifiers to kegg compound identifiers.

Created: 2016-06-21

Credits: User Kristina Hettne

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