Pack: Towards Genotype-Phenotype Correlations

Created: 2009-04-08 13:14:54      Last updated: 2009-08-11 14:50:01
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Title: Towards Genotype-Phenotype Correlations


Information Description

It is increasingly common to combine Microarray and Quantitative Trait Loci data to aid the search for candidate genes responsible for phenotypic variation. Workflows provide a means of systematically processing large datasets, and represent a framework for the re-use and the explicit declaration of experimental methods. In this pack is a paper which describes the issues facing the manual analysis of microarray and QTL data for the discovery of candidate genes underlying complex phenotypes.  Our methodology was applied to a use case of resistance to African trypanosomiasis in the mouse.  Workflows developed in this investigation, including a guide to loading and executing them with example data, are available within this pack.

Supplimentary information is provided in this pack.

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  • Internal item

    File: A Systematic Strategy for Large-Scale Analysis of Genotype-Phenotype Correlations: Identification of candidate genes involved in African Trypanosomiasis (Paul Fisher)

    Added by Paul Fisher ... more than 1 year ago (2009-04-08 13:23:31)

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  • Internal item

    File: Authors table (Paul Fisher)

    Added by Paul Fisher ... more than 1 year ago (2009-04-08 13:36:23)

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  • Internal item

    File: Candidate Gene protocol (Paul Fisher)

    Added by Paul Fisher ... more than 1 year ago (2009-04-08 13:27:53)

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  • Internal item

    File: Ensembl database release (Paul Fisher)

    Added by Paul Fisher ... more than 1 year ago (2009-04-08 18:04:50)

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  • Internal item

    File: Ensembl gene report (Paul Fisher)

    Added by Paul Fisher ... more than 1 year ago (2009-04-08 19:30:29)

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  • Internal item

    File: Kegg gene descriptions (Paul Fisher)

    Added by Paul Fisher ... more than 1 year ago (2009-04-08 18:06:41)

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  • Internal item

    File: Kegg pathway descriptions (Paul Fisher)

    Added by Paul Fisher ... more than 1 year ago (2009-04-08 19:28:17)

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  • Internal item

    File: Kegg pathway identifiers (Paul Fisher)

    Added by Paul Fisher ... more than 1 year ago (2009-04-08 19:29:04)

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  • Internal item

    File: Kegg Pathway release (Paul Fisher)

    Added by Paul Fisher ... more than 1 year ago (2009-04-08 19:25:32)

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  • Internal item

    File: Kegg pathways and genes (Paul Fisher)

    Added by Paul Fisher ... more than 1 year ago (2009-04-08 19:26:46)

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  • Internal item

    Workflow: KEGG pathways common to both QTL and microarray based investigations (Paul Fisher)

    Comment

    Common pathways

    Added by Paul Fisher ... more than 1 year ago (2009-04-08 13:18:55)

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  • Internal item

    File: Kegg-Uniprot-Entrez cross-references (Paul Fisher)

    Added by Paul Fisher ... more than 1 year ago (2009-04-08 19:24:07)

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  • Internal item

    Workflow: Mouse Microarray Analysis (Paul Fisher)

    Comment

    Microarray workflow

    Added by Paul Fisher ... more than 1 year ago (2009-04-08 13:18:26)

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  • Internal item

    Pack: Pathway to Phenotype using Text Mining (Paul Fisher)

    Added by Paul Fisher ... more than 1 year ago (2009-08-11 14:50:01)

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  • Internal item

    Workflow: Pathways and Gene annotations for QTL region (Paul Fisher)

    Comment

    QTL workflow

    Added by Paul Fisher ... more than 1 year ago (2009-04-08 13:17:26)

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  • Internal item

    File: Re-sequenced Daxx gene info (Paul Fisher)

    Added by Paul Fisher ... more than 1 year ago (2009-04-08 17:54:10)

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  • Internal item

    File: Table of SNP sequenceing results (Paul Fisher)

    Added by Paul Fisher ... more than 1 year ago (2009-04-08 13:29:50)

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  • Internal item

    File: Tir1 QTL - Day 3 Microarray intersecting pathways (Paul Fisher)

    Added by Paul Fisher ... more than 1 year ago (2009-04-08 17:56:29)

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  • Internal item

    File: Tir1 QTL - microarray day 7 intersecting pathways (Paul Fisher)

    Added by Paul Fisher ... more than 1 year ago (2009-04-08 17:58:14)

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  • External item

    External: Link - (http://www.slideshare.net/fisherp/a-systematic-approach-to-genotypephenotype-correlations)

    Added by Paul Fisher ... more than 1 year ago (2009-08-10 12:38:06)



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