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Created: 03/10/07 @ 18:36:05 | Last updated: 03/12/09 @ 16:20:33 License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes in probesets from and AffyMetrix micorarray experiment and returns: the genes ; gene start and end positions; chromosome where genes reside; ensembl trasncripts; SwissProt ids; affy probeset identifiers for chips Mouse430_2 and Mouse430a_2.
Example ids from the Mouse430_2 affymetrix array are as follows (newline separated):
1447227_at
1440624_at
1436240_at
1454904_at
1435665_at
1418148_at
1429831_at
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Created: 03/10/07 @ 18:36:09 | Last updated: 22/11/07 @ 16:03:15
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License: Creative Commons Attribution-No Derivative Works 3.0 Unported License
This is a revised workflow for the Graves disease scenario gene annotation pipeline used in the myGrid project. The workflow had to be re-written due to the loss of the services invoked in the original workflow.
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Created: 08/02/08 @ 14:30:17 | Last updated: 03/12/09 @ 16:50:29
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes in probesets from and AffyMetrix Affy HG U133A micorarray experiment and returns: genes ; gene start and end positions; chromosome where genes reside; ensembl trasncripts; SwissProt ids. The final output of the workflow is a list of candidate pathways which are linked to the genes expressed in the microarray data.
Example input for this workflow is:
212283_at
221634_at
220399_at
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Created: 26/01/09 @ 18:06:12 | Last updated: 14/12/09 @ 12:05:21
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow gets a series of information relating to a list of KEGG genes supplied to it. It also removes any null values from a list of strings.
Example input for this workflow is given below (new line separated):
mmu:13163
hsa:1616
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Created: 06/03/09 @ 17:18:13 | Last updated: 03/12/09 @ 16:59:11
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License: Creative Commons Attribution-No Derivative Works 3.0 Unported License
This workflow searches for genes obtained from affy_ath1 affymetrix probeset identifiers. The Entrez and UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to searcg for pathways in the KEGG pathway database.
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Created: 03/03/09 @ 13:17:27 | Last updated: 02/11/09 @ 10:13:38
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow searches OMIM for entries associated with a particular disease in OMIM, returns the IDs and maps them to Kegg Gene IDs. For each gene, it then gets the description and any corresponding pathways those genes are involved with
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Created: 08/06/09 @ 18:39:38 | Last updated: 14/12/09 @ 11:51:20
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow converts a list of NCBI gi numbers and converts them to a list of KEGG genes. Those KEGG gene ids are subsequently turned into KEGG pathway identifiers and descriptions. It also removes any null values from a list of strings.
Example input for this workflow is as follows (new line separated):
gi:215422388
gi:120407068
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Created: 10/08/09 @ 13:19:36 | Last updated: 10/08/09 @ 13:24:28
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow calculates the cosine vector space between two sets of corpora. The workflow then removes any null values from the output.
The result is a cosine vector score between 0 and 1, showing the significance of any links between one concept (e.g. pathway) to another (e.g. phenotype).
A score of 0 means there is no or an undetermined correlation between the two concepts. A score approaching 1 represents positive correlation.
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Created: 10/08/09 @ 13:31:07 | Last updated: 10/08/09 @ 13:32:21
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes in a document containg text and removes any non-ascii characters. The cleaned text is then sent to a service in Dresden, to extract all scientific terms. These terms represent a concept profile for the input concpet. Any null values are also removed.
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Created: 08/07/09 @ 16:28:34
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License: Creative Commons Attribution-No Derivative Works 3.0 Unported License
This workflow searches for genes which are found to be differentially expressed in a microarray study using Arabidopsis thaliana. The workflow requires an input of a list of differentially expressed AffyMetrix Probeset identifiers. Data is then extracted from BioMart to annotate each of the genes. The UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to searcg for pathways in the KEGG pathway database.
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Created: 19/08/09 @ 16:05:20
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes in a tab separated file, and then parses specific rows and columns from the file into an Ondex Graph. Additional prarameters are provided, though these are optional:
graphId Long the ID of the Graph (REQUIRED)
input String the plugin input (REQUIRED)
skip Integer How many rows to skip at begin of document (Optional). Default value is 22.
fromCol Integer Index of concept parser id for from concept. Default value is 0. (REQUIRED)
toCol Integer Index of concept par...
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Created: 07/09/09 @ 15:00:01 | Last updated: 09/09/09 @ 14:21:48
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
Accepts a chromosome eg. 1 and returns the ensembl gene ids for that chromosome
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Created: 20/11/09 @ 14:04:37 | Last updated: 20/11/09 @ 14:04:39
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow searches for genes which reside in a QTL (Quantitative Trait Loci) region in the Pig, Sus scrofa. The workflow requires an input of: a chromosome name or number; a QTL start base pair position; QTL end base pair position. Data is then extracted from BioMart to annotate each of the genes found in this region. The Entrez and UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to searcg for pathways in the KEGG pathway ...
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Created: 23/11/09 @ 18:09:47
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
Query all the gene expression data in a caArray experiment. Returns a evenly divided gene expression data set with corresponding class information. They ca be later used as training and test data set in many classification algorithms.Query all the gene expression data in a caArray experiment. Returns a evenly divided gene expression data set with corresponding class information. They can be later used as training and test data set in many classification algorithms.
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Created: 04/02/10 @ 12:47:16 | Last updated: 04/02/10 @ 12:48:11
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow gets a list of gene ids (number depending on Ret_Max_value variable) for Homo sapiens. The species may be changed according to that desired, by altering the term_value string constant
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Created: 13/03/10 @ 08:17:39
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
Find pathways in which all the genes in the list are involved. For each pathway draw the pathway diagram.for each protein draw a diagram of the Kegg pathway that its protein is involved in and where available visualise the structures
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Created: 15/03/10 @ 08:43:31
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow retrieves data from the MaxD microarray database and calculates the frequencies of gene expression levels using an R script
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Created: 16/03/10 @ 16:33:35
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
No description
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Created: 15/04/10 @ 12:22:12 | Last updated: 15/04/10 @ 12:22:13
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes in Entrez gene ids then adds the string "ncbi-geneid:" to the start of each gene id. These gene ids are then cross-referenced to KEGG gene ids. Each KEGG gene id is then sent to the KEGG pathway database and its relevant pathways returned.
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Created: 30/04/10 @ 16:09:29 | Last updated: 30/04/10 @ 16:12:02
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes a list of KEGG gene identifiers and supplies descriptions associated to said genes + pathways including all genes and the descriptions associated to said pathways.
The list_to_string local beanshell scripts merely transform a given list into a string of unique not-null elements separated by new lines (for batch btit use).
Note that the input is a real taverna list : multiple values must be declared as multiple values instead of a single string value with distinct identif...
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Created: 05/07/10 @ 13:14:36 | Last updated: 26/01/11 @ 16:57:39
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes in a list of gene names and searches the PubMed database for corresponding articles. Any matches to the genes are then retrieved (abstracts only). These abstracts are then returned to the user.
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Created: 15/11/10 @ 12:08:18 | Last updated: 16/11/10 @ 16:07:49
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow searches for genes which reside in a QTL (Quantitative Trait Loci) region in the mouse, Mus musculus. The workflow requires an input of: a chromosome name or number; a QTL start base pair position; QTL end base pair position. Data is then extracted from BioMart to annotate each of the genes found in this region. The Entrez and UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to searcg for pathways in the KEGG path...
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Created: 15/11/10 @ 12:25:01 | Last updated: 15/11/10 @ 12:28:12
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow searches for genes which were found to be differentially expressed from a microarray study in the mouse, Mus musculus. The workflow requires an input of gene ref_seq identifiers. Data is then extracted from BioMart to annotate each of the genes found for each ref_seq id. The Entrez and UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to search for pathways in the KEGG pathway database.
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Created: 21/01/11 @ 16:56:47 | Last updated: 21/01/11 @ 16:58:50
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow searches for genes which reside in a QTL (Quantitative Trait Loci) region in Cow, Bos taurus. The workflow requires an input of: a chromosome name or number; a QTL start base pair position; QTL end base pair position. Data is then extracted from BioMart to annotate each of the genes found in this region. The Entrez and UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to searcg for pathways in the KEGG pathway data...
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Created: 10/02/11 @ 16:10:52 | Last updated: 18/02/11 @ 13:47:08
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes in a list of gene names and KEGG pathway descriptions, and searches the PubMed database for corresponding articles. Any matches to the genes are then retrieved (abstracts only). These abstracts are then used to calculate a cosine vector space between two sets of corpora (gene and phenotype, or pathway and phenotype). The workflow counts the number of articles in the pubmed database in which each term occurs, and identifies the total number of articles in the entire PubMe...
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Created: 17/03/11 @ 11:10:28 | Last updated: 30/08/11 @ 10:40:14
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow searches for genes which reside in a QTL (Quantitative Trait Loci) region in Human, Homo sapiens. The workflow requires an input of: a chromosome name or number; a QTL start base pair position; QTL end base pair position. Data is then extracted from BioMart to annotate each of the genes found in this region. The Entrez and UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to searcg for pathways in the KEGG pathway ...
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Created: 29/03/11 @ 14:55:31 | Last updated: 29/03/11 @ 15:00:22
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow functions for matching a set of genes as a part of whole gene data set and aim to extract the subset as a separate list.
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Created: 27/01/11 @ 17:03:03 | Last updated: 12/05/11 @ 13:31:41
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow retrieves all genes on human chromosome 22 that are associated with a disease and aligns the upstream regions with mouse and rat homologues. The alignments are plotted and corresponding sequence ids are also returned.Using Biomart and EMBOSS soaplab services, This workflow retrieves a number of sequences from 3 species: mouse, human, rat; align them, and returns a plot of the alignment result. Corresponding sequence ids are also returned.
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Created: 30/06/11 @ 15:26:13 | Last updated: 04/07/11 @ 16:51:41
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow carries out alignments using TCoffee and ClustalW2 for a set of non-redundant proteins where the starting point is a particular genomic coding sequence representing only one member of the gene family in a given species.
For the BioExtract Server implementation, the necessary steps for accomplishing this task involve:
1. Selecting the NCBI tblastx tool and providing the accession number of the known nucleotide sequence record as input.
2. The output from ...
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Created: 19/11/09 @ 18:18:52 | Last updated: 02/09/11 @ 11:44:57
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow searches for genes which reside in a QTL (Quantitative Trait Loci) region in the mouse, Mus musculus. The workflow requires an input of: a chromosome name or number; a QTL start base pair position; QTL end base pair position. Data is then extracted from BioMart to annotate each of the genes found in this region. The Entrez and UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to searcg for pathways in the KEGG path...
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Created: 05/10/11 @ 05:04:40 | Last updated: 05/10/11 @ 05:04:42
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This is a workflow which allows one to extract gene sequence information using the accession number as the input. Multiple outputs include a file output of sequence header information, as well as one output window of base pair count, ratios and gene sequence.
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Created: 12/01/12 @ 09:46:31 | Last updated: 12/01/12 @ 14:54:37
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow accepts a list of genbank gene identifiers and returns descriptions of gene functions and a list of all pathways each gene is involved in, according to the KEGG database.
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Created: 15/01/12 @ 10:23:33 | Last updated: 17/01/12 @ 15:22:07
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow extracts a column of RefSeq gene IDs from a CSV file and then converts them to Unigene identifiers
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Created: 16/01/12 @ 15:31:40
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow returns a list of pathways gene products are involved in, along with their descriptions and Gene Ontology annotations
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Created: 08/02/12 @ 16:08:08 | Last updated: 08/02/12 @ 16:08:09
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
Defines regions and genes from associated SNPs
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Created: 08/02/12 @ 16:14:17 | Last updated: 08/02/12 @ 16:14:47
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
Produces a gene list from the Associated Region XML file
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Created: 08/12/10 @ 11:55:03 | Last updated: 01/02/11 @ 11:33:11
This pack contains workflows to navigate from candidate Quantitative Trait genes and pathways to a given phenotype.
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Created: 05/10/11 @ 04:58:33 | Last updated: 05/10/11 @ 06:11:56
This workflow and pack were designed for a class project. The Kepler based workflow allows one to extract specific information from a gene sequence by using the accession ID as input. By using two web services created for the DNA Data Bank of Japan (DDBJ, http://www.xml.nig.ac.jp/wabi/Method?serviceName=DDBJ&mode=methodList&lang=en), one can extract the sequence header information as an output file, as well as retrieve the sequence, base pair count, and base pair ratios in...
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Created: 02/12/11 @ 09:31:26 | Last updated: 02/12/11 @ 10:21:03
This pack contains (references to) the workflows for GWAS analysis by workflows that perform pathway and GO analysis and biosemantics data interpretation (a special form of text mining).
This pack aggregates the deliverable materials for month 8 for Work Package 6. The workflows have not been published in the scientific domain yet, so its content cannot yet be made public. They are available upon request, in particular for reviewers. Please contact Kristina Hettne or Marco Roos (see credit...
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Created: 08/04/09 @ 13:27:20
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This protocol provides details on how to identify candidate genes from the returned workflow results.
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Created: 08/04/09 @ 17:53:46 | Last updated: 10/08/09 @ 12:30:59
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This spreadsheet contains information about the re-sequencing of the daxx gene, identified as a candidate QTg for the African Trypanosomiasis resiatance phenotype. This file is related to the paper: http://www.ncbi.nlm.nih.gov/pubmed/17709344
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Created: 08/04/09 @ 17:56:10
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This spreadhseet contains all of the intersecting pathways between the Tir1 QTL and day 3 differentially expressed genes
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Created: 08/04/09 @ 17:57:57
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This spreadhseet contains all of the intersecting pathways between the Tir1 QTL and day 7 differentially expressed genes
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Created: 08/04/09 @ 18:00:35 | Last updated: 10/08/09 @ 12:12:09
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
The release of the Ensembl database used to identify genes in Tir1 QTL region.
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Created: 08/04/09 @ 18:06:23 | Last updated: 10/08/09 @ 12:10:07
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a list of KEGG gene descriptions, for each KEGG gene identified within the Tir1 QTL region.
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Created: 08/04/09 @ 19:30:15 | Last updated: 10/08/09 @ 11:05:59
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains all genes identified in the Tir1 QTL region.
Each gene is (if available) associated with an Entrez, UniProt, External Gene Id, Affymetrix probeset identifers (mouse_430_A chip), and Ensembl identifers for genes and their transcripts.
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Created: 10/08/09 @ 16:00:45
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This excel file contains a list of genes linked to the resistance to African trypanosomiasis in the mouse. Genes from the Tir1 QTL were used in a search through PubMed. The results were then correlated to the trypanosomiasis resistance phenotype. The higher the score (and ranking) the more related to the phenotype the gene is likely to be. This is based on the co-occurrence of terms within the gene and phentoype corpora.
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Created: 11/08/09 @ 13:05:07 | Last updated: 11/08/09 @ 13:06:51
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This file contains a list of all terms extracted from the phenotype corpus, relating to African trypanosomiasis resistance in the mouse model.
These terms were extracted using the following service: http://gopubmed4.biotec.tu-dresden.de/GoPubMedTermGenerationService/services/GoPubMedTermGeneration?wsdl
These terms represent the concept profile for the phenotype.
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Created: 17/03/11 @ 10:56:15 | Last updated: 17/03/11 @ 11:16:53
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This zip file contains the results of running a QTL workflow for Bilateral Perisylvian Polymicrogyria in human (homo sapiens). Provided are a list of candidate QTL genes (QTg) and their corresponding KEGG pathways. Each gene and pathway have been subsequently run through a series of text mining workflows to determine the significance each may play in relation to Bilateral Perisylvian Polymicrogyria.
If you want to help me identify candidate genes for this disorder, please get i...
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Created: 01/04/11 @ 09:08:45 | Last updated: 01/04/11 @ 09:08:51 License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a list or affymetrix probest identifiers for Human gene expression data relating to the: Impact of NRSF variant over-expression in SK-N-AS human neuroblastoma cells (http://www.ebi.ac.uk/arrayexpress/browse.html?keywords=E-GEOD-22467&expandefo=on)
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