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Created: 04/12/07 @ 23:43:01 | Last updated: 04/12/07 @ 23:45:25
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
No description
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Created: 03/10/07 @ 18:36:22 | Last updated: 05/03/08 @ 13:59:55 License: Creative Commons Attribution-No Derivative Works 3.0 Unported License
This workflow retrieves KEGG pathway id and image given a KEGG gene id.
e.g hsa:6402 or eco:b0002
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Created: 08/05/08 @ 15:25:29 | Last updated: 12/05/08 @ 09:01:37
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes in a CDNA raw file and a normalisation method then returns a series of images/graphs which represent the same output obtained using the R and bioconductor. Also retruned by this workflow are a list of the top differentialy expressed genes (size dependant on the number specified as input - geneNumber), which are then used to find the candidate pathways which may be influencing the observed changes in the microarray data. By identifying the candidate pathways, more detailed...
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Created: 26/01/09 @ 18:06:12 | Last updated: 14/12/09 @ 12:05:21
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow gets a series of information relating to a list of KEGG genes supplied to it. It also removes any null values from a list of strings.
Example input for this workflow is given below (new line separated):
mmu:13163
hsa:1616
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Created: 06/03/09 @ 17:18:13 | Last updated: 03/12/09 @ 16:59:11
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License: Creative Commons Attribution-No Derivative Works 3.0 Unported License
This workflow searches for genes obtained from affy_ath1 affymetrix probeset identifiers. The Entrez and UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to searcg for pathways in the KEGG pathway database.
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Created: 04/06/09 @ 18:41:36 | Last updated: 07/01/10 @ 15:31:37
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
this is a simplified version of Paul's workflow (linked?) that is designed to be provenance-friendly
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Created: 10/08/09 @ 13:19:36 | Last updated: 10/08/09 @ 13:24:28
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow calculates the cosine vector space between two sets of corpora. The workflow then removes any null values from the output.
The result is a cosine vector score between 0 and 1, showing the significance of any links between one concept (e.g. pathway) to another (e.g. phenotype).
A score of 0 means there is no or an undetermined correlation between the two concepts. A score approaching 1 represents positive correlation.
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Created: 10/08/09 @ 13:31:07 | Last updated: 10/08/09 @ 13:32:21
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes in a document containg text and removes any non-ascii characters. The cleaned text is then sent to a service in Dresden, to extract all scientific terms. These terms represent a concept profile for the input concpet. Any null values are also removed.
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Created: 08/07/09 @ 16:28:34
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License: Creative Commons Attribution-No Derivative Works 3.0 Unported License
This workflow searches for genes which are found to be differentially expressed in a microarray study using Arabidopsis thaliana. The workflow requires an input of a list of differentially expressed AffyMetrix Probeset identifiers. Data is then extracted from BioMart to annotate each of the genes. The UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to searcg for pathways in the KEGG pathway database.
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Created: 19/08/09 @ 16:03:07
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow parses a KEGG species database into an Ondex Graph
graphId - the ID of the Graph.
inputDir - the plugin input directory
Species - Use this parameter to specify the species to be loaded from the kegg database. Default value is all.
ParseSequences - KEGG species code. Default value is false (boolean)
ImportOrthologFillers - Import Ortholog Pathway Fillers. Default value is false (boolean)
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Created: 20/11/09 @ 14:04:37 | Last updated: 20/11/09 @ 14:04:39
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow searches for genes which reside in a QTL (Quantitative Trait Loci) region in the Pig, Sus scrofa. The workflow requires an input of: a chromosome name or number; a QTL start base pair position; QTL end base pair position. Data is then extracted from BioMart to annotate each of the genes found in this region. The Entrez and UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to searcg for pathways in the KEGG pathway ...
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Created: 10/03/10 @ 17:15:47 | Last updated: 10/03/10 @ 17:18:47
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow gets a series of information relating to a list of KEGG pathways supplied to it. It also removes any null values from a list of strings. Example input: path:mmu04010 path:mmu05014
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Created: 30/04/10 @ 16:09:29 | Last updated: 30/04/10 @ 16:12:02
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes a list of KEGG gene identifiers and supplies descriptions associated to said genes + pathways including all genes and the descriptions associated to said pathways.
The list_to_string local beanshell scripts merely transform a given list into a string of unique not-null elements separated by new lines (for batch btit use).
Note that the input is a real taverna list : multiple values must be declared as multiple values instead of a single string value with distinct identif...
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Created: 03/03/09 @ 13:17:27 | Last updated: 02/11/09 @ 10:13:38
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow searches OMIM for entries associated with a particular disease in OMIM, returns the IDs and maps them to Kegg Gene IDs. For each gene, it then gets the description and any corresponding pathways those genes are involved with
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Created: 15/11/10 @ 12:08:18 | Last updated: 16/11/10 @ 16:07:49
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow searches for genes which reside in a QTL (Quantitative Trait Loci) region in the mouse, Mus musculus. The workflow requires an input of: a chromosome name or number; a QTL start base pair position; QTL end base pair position. Data is then extracted from BioMart to annotate each of the genes found in this region. The Entrez and UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to searcg for pathways in the KEGG path...
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Created: 15/11/10 @ 12:25:01 | Last updated: 15/11/10 @ 12:28:12
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow searches for genes which were found to be differentially expressed from a microarray study in the mouse, Mus musculus. The workflow requires an input of gene ref_seq identifiers. Data is then extracted from BioMart to annotate each of the genes found for each ref_seq id. The Entrez and UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to search for pathways in the KEGG pathway database.
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Created: 15/11/10 @ 12:30:21 | Last updated: 15/11/10 @ 12:30:59
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes in two lists of KEGG pathway ids. These are designed to come from pathways found from genes in a QTL (Quantitative Trait Loci) region, and from pathways found from genes differentially expressed in a microarray study. By identifying the intersecting pathways from both studies, a more informative picture is obtained of the candidate processes involved in the expression of a phenotype
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Created: 08/12/10 @ 11:47:10 | Last updated: 11/01/11 @ 12:00:16
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes in a list of KEGG pathway descriptions and searches the PubMed database for corresponding articles. Any matches to the pathways are then retrieved (abstracts only). These abstracts are then returned to the user.
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Created: 21/01/11 @ 16:56:47 | Last updated: 21/01/11 @ 16:58:50
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow searches for genes which reside in a QTL (Quantitative Trait Loci) region in Cow, Bos taurus. The workflow requires an input of: a chromosome name or number; a QTL start base pair position; QTL end base pair position. Data is then extracted from BioMart to annotate each of the genes found in this region. The Entrez and UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to searcg for pathways in the KEGG pathway data...
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Created: 08/02/11 @ 13:04:06 | Last updated: 10/02/11 @ 16:01:41
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes in a list of gene names and searches the PubMed database for corresponding articles. Any matches to the genes are then retrieved (abstracts only). These abstracts are then returned to the user.
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Created: 10/02/11 @ 16:10:52 | Last updated: 18/02/11 @ 13:47:08
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes in a list of gene names and KEGG pathway descriptions, and searches the PubMed database for corresponding articles. Any matches to the genes are then retrieved (abstracts only). These abstracts are then used to calculate a cosine vector space between two sets of corpora (gene and phenotype, or pathway and phenotype). The workflow counts the number of articles in the pubmed database in which each term occurs, and identifies the total number of articles in the entire PubMe...
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Created: 17/03/11 @ 11:10:28 | Last updated: 30/08/11 @ 10:40:14
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow searches for genes which reside in a QTL (Quantitative Trait Loci) region in Human, Homo sapiens. The workflow requires an input of: a chromosome name or number; a QTL start base pair position; QTL end base pair position. Data is then extracted from BioMart to annotate each of the genes found in this region. The Entrez and UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to searcg for pathways in the KEGG pathway ...
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Created: 24/03/11 @ 15:14:48 | Last updated: 24/03/11 @ 15:37:48
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow searches for genes found from a set of differentially expressed probestes, in Human, Homo sapiens. The workflow requires an input human affymetrix probeset identifiers. Data is then extracted from BioMart to annotate each of the genes found in this region. The Entrez and UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to searcg for pathways in the KEGG pathway database.
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Created: 27/05/11 @ 11:06:11 | Last updated: 27/05/11 @ 11:06:52
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow searches for genes which reside in a QTL (Quantitative Trait Loci) region in rice, Oryza sativa. The workflow requires an input of: a chromosome name or number; a QTL start base pair position; QTL end base pair position. Data is then extracted from BioMart to annotate each of the genes found in this region. The Entrez and UniGene identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to searcg for pathways in the KEGG pathway d...
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Created: 08/04/09 @ 13:14:54 | Last updated: 11/08/09 @ 14:50:01
It is increasingly common to combine Microarray and Quantitative Trait Loci data to aid the search for candidate genes responsible for phenotypic variation. Workflows provide a means of systematically processing large datasets, and represent a framework for the re-use and the explicit declaration of experimental methods. In this pack is a paper which describes the issues facing the manual analysis of microarray and QTL data for the discovery of candidate genes underlying complex phenotypes.&n...
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Created: 10/08/09 @ 13:01:47 | Last updated: 11/08/09 @ 14:51:31
This pack contains a list of workflows and result files obtained from the analysis of candidate pathways believed to play a role in resistance to African Trypanosomiasis in the mouse model organism.
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Created: 11/08/09 @ 14:44:16 | Last updated: 11/08/09 @ 14:52:12
This pack is for investigating links between the genotype of an organisms to possible pathways. This constitutes half of the pathway-driven approach, genotype to pathway, and pathway to phenotype.
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Created: 08/12/10 @ 11:55:03 | Last updated: 01/02/11 @ 11:33:11
This pack contains workflows to navigate from candidate Quantitative Trait genes and pathways to a given phenotype.
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Created: 16/02/11 @ 12:49:21 | Last updated: 16/02/11 @ 15:26:36
This pack contains the workflows and data relating to Trichuriasis induced colitis.
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Created: 16/11/10 @ 16:20:43 | Last updated: 23/09/11 @ 10:55:08
This pack contains freely accessible data for scientific researchers to try and identify key genes linked to Bilateral Perisylvian Polymicrogyria. For those who want more information about this condition before they download the data, please see this link, which describes the condition and traits: http://omim.org/entry/300388?search=bilateral%20perisylvian%20polymicrogyria
The results conatined within this pack are the output from running a scientific workflow that identifies candidate genes...
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Created: 08/04/09 @ 13:27:20
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This protocol provides details on how to identify candidate genes from the returned workflow results.
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Created: 08/04/09 @ 19:28:52 | Last updated: 10/08/09 @ 11:03:00
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a list of KEGG pathway identifiers, derived from a list of Ensembl genes found to be located with a given QTL/chromosomal region in the mouse. These genes are located in the Tir1 QTL.
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Created: 08/04/09 @ 19:27:55 | Last updated: 10/08/09 @ 11:29:34
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a list of KEGG pathway descriptions, identified from genes found within the Tir1 QTL region (for African Trypanosomiasis). Each pathway may contain multiple genes from within the QTL region.
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Created: 08/04/09 @ 19:26:26 | Last updated: 10/08/09 @ 11:41:55
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a list of all genes found within the Tir1 QTL region. These are represented as KEGG gene identifiers. Each gene is listed in tab deliminated format along with all KEGG pathway ids in which the gene is involved. These are given as KEGG pathway identifiers. Each gene may be included in zero or more pathways, with multiple instances of the same pathway being included in the file (due to multiple genes included in a single pathway).
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Created: 08/04/09 @ 19:25:05 | Last updated: 10/08/09 @ 12:06:18
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains the version of the KEGG pathway database used in the analysis of the Tir1 QTL region
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Created: 10/08/09 @ 15:55:24
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This excel file contains a list of all pathways found to be differentially expressed at day 7 post infection in the trypanosomiasis resistance phenotype, which contain genes in the Tir1 QTL.
The pathways in this file have been ranked according to the scores obtained after calculating a cosine vector value against the trypanosomiasis resistance phenotype. The higher the score, the more closely linked to a phentype a given pathway is.
This allows each pathway to be ranked giving biologists a ...
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Created: 11/08/09 @ 14:08:41 | Last updated: 11/08/09 @ 14:15:58
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains all the abstracts for pathways found to be differentially expressed at day 7 post infection and intersect the Tir1 QTL region, from the African Trypanosomiasis project.
Each pathway is listed as ">> [Pathway Name]", together with a PubMed identifier, date, and abstract for each article. Each pathway has been restricted to 500 abstracts, and is given in the date range 31/12/2007 to 01/01/2009. Note, some pathways do not have any abstracts available due to th...
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Created: 16/02/11 @ 15:16:17 | Last updated: 16/02/11 @ 15:16:24
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This zip file contains the results of workflow runs for: identifying genes in each of the 7 QTL regions for Trichuris muris infection; identifying genes differentially expressed in mice challenged with Trichuris muris; and Text mining results (including cosine vector scores and Term Enrichment values).
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Created: 17/03/11 @ 10:56:15 | Last updated: 17/03/11 @ 11:16:53
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This zip file contains the results of running a QTL workflow for Bilateral Perisylvian Polymicrogyria in human (homo sapiens). Provided are a list of candidate QTL genes (QTg) and their corresponding KEGG pathways. Each gene and pathway have been subsequently run through a series of text mining workflows to determine the significance each may play in relation to Bilateral Perisylvian Polymicrogyria.
If you want to help me identify candidate genes for this disorder, please get i...
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Created: 01/04/11 @ 09:12:28 | Last updated: 01/04/11 @ 09:12:40
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Attributions: License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a list processed for Human gene expression CEL files relating to the: Impact of NRSF variant over-expression in SK-N-AS human neuroblastoma cells (http://www.ebi.ac.uk/arrayexpress/browse.html?keywords=E-GEOD-22467&expandefo=on).
The CEL files were analysed using the MADAT Taverna workflow available on myExperiment:
http://www.myexperiment.org/workflows/2002.html
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