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Created: 19/11/09 @ 18:18:52 | Last updated: 02/09/11 @ 11:44:57
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow searches for genes which reside in a QTL (Quantitative Trait Loci) region in the mouse, Mus musculus. The workflow requires an input of: a chromosome name or number; a QTL start base pair position; QTL end base pair position. Data is then extracted from BioMart to annotate each of the genes found in this region. The Entrez and UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to searcg for pathways in the KEGG path...
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Created: 03/10/07 @ 18:35:55 | Last updated: 26/11/09 @ 17:34:24 License: Creative Commons Attribution-No Derivative Works 3.0 Unported License
This workflow takes in a CEL file and a normalisation method then returns a series of images/graphs which represent the same output obtained using the MADAT software package (MicroArray Data Analysis Tool) [http://www.bioinf.manchester.ac.uk/MADAT/index.html]. Also returned by this workflow are a list of the top differentialy expressed genes (size dependant on the number specified as input - geneNumber), which are then used to find the candidate pathways which may be influencing the observed ...
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Created: 04/12/09 @ 16:04:38 | Last updated: 30/11/10 @ 12:18:53
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License: Creative Commons Attribution 3.0 Unported License
This workflow takes in Entrez gene ids then adds the string "ncbi-geneid:" to the start of each gene id. These gene ids are then cross-referenced to KEGG gene ids. Each KEGG gene id is then sent to the KEGG pathway database and its relevant pathways returned.
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Created: 24/11/09 @ 17:14:43 | Last updated: 03/12/09 @ 15:28:49 License: Creative Commons Attribution-No Derivative Works 3.0 Unported License
This workflow takes in two lists of KEGG pathway ids. These are designed to come from pathways found from genes in a QTL (Quantitative Trait Loci) region, and from pathways found from genes differentially expressed in a microarray study. By identifying the intersecting pathways from both studies, a more informative picture is obtained of the candidate processes involved in the expression of a phenotype.
Example input for this workflow is given below (as newline separated values).
qt...
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Created: 03/10/07 @ 18:36:05 | Last updated: 03/12/09 @ 16:20:33 License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes in probesets from and AffyMetrix micorarray experiment and returns: the genes ; gene start and end positions; chromosome where genes reside; ensembl trasncripts; SwissProt ids; affy probeset identifiers for chips Mouse430_2 and Mouse430a_2.
Example ids from the Mouse430_2 affymetrix array are as follows (newline separated):
1447227_at
1440624_at
1436240_at
1454904_at
1435665_at
1418148_at
1429831_at
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Created: 27/11/07 @ 11:53:11 | Last updated: 28/11/07 @ 12:58:38
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
Takes a KEGG gene identifier, e.g. sce:YAL038W (yeast pyruvate kinase) and converts to the corresponding Swissprot identifier.
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Created: 04/12/07 @ 23:43:01 | Last updated: 04/12/07 @ 23:45:25
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
No description
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Created: 08/02/08 @ 14:17:23 | Last updated: 13/02/09 @ 11:29:52
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes in a CEL file and a normalisation method then returns a series of images/graphs which represent the same output obtained using the MADAT software package (MicroArray Data Analysis Tool) http://www.bioinf.manchester.ac.uk/MADAT/index.html. Also retruned by this workflow are a list of the top differentialy expressed genes (size dependant on the number specified as input - geneNumber), which are then used to find the candidate pathways which may be influencing the observed ch...
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Created: 08/02/08 @ 14:30:17 | Last updated: 03/12/09 @ 16:50:29
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes in probesets from and AffyMetrix Affy HG U133A micorarray experiment and returns: genes ; gene start and end positions; chromosome where genes reside; ensembl trasncripts; SwissProt ids. The final output of the workflow is a list of candidate pathways which are linked to the genes expressed in the microarray data.
Example input for this workflow is:
212283_at
221634_at
220399_at
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Created: 03/10/07 @ 18:36:22 | Last updated: 05/03/08 @ 13:59:55 License: Creative Commons Attribution-No Derivative Works 3.0 Unported License
This workflow retrieves KEGG pathway id and image given a KEGG gene id.
e.g hsa:6402 or eco:b0002
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Created: 08/05/08 @ 15:25:29 | Last updated: 12/05/08 @ 09:01:37
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes in a CDNA raw file and a normalisation method then returns a series of images/graphs which represent the same output obtained using the R and bioconductor. Also retruned by this workflow are a list of the top differentialy expressed genes (size dependant on the number specified as input - geneNumber), which are then used to find the candidate pathways which may be influencing the observed changes in the microarray data. By identifying the candidate pathways, more detailed...
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Created: 26/01/09 @ 18:06:12 | Last updated: 14/12/09 @ 12:05:21
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow gets a series of information relating to a list of KEGG genes supplied to it. It also removes any null values from a list of strings.
Example input for this workflow is given below (new line separated):
mmu:13163
hsa:1616
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Created: 03/03/09 @ 13:17:27 | Last updated: 02/11/09 @ 10:13:38
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow searches OMIM for entries associated with a particular disease in OMIM, returns the IDs and maps them to Kegg Gene IDs. For each gene, it then gets the description and any corresponding pathways those genes are involved with
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Created: 06/03/09 @ 17:18:13 | Last updated: 03/12/09 @ 16:59:11
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License: Creative Commons Attribution-No Derivative Works 3.0 Unported License
This workflow searches for genes obtained from affy_ath1 affymetrix probeset identifiers. The Entrez and UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to searcg for pathways in the KEGG pathway database.
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Created: 18/03/09 @ 14:49:02 | Last updated: 18/03/09 @ 14:51:28
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow accepts looks up drug identifiers from KEGG given a pathway identifier. You can enter a pathway ID in the form path:map07026
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Created: 28/04/09 @ 07:48:40
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
No description
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Created: 28/04/09 @ 07:55:10
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
No description
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Created: 04/06/09 @ 18:41:36 | Last updated: 07/01/10 @ 15:31:37
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
this is a simplified version of Paul's workflow (linked?) that is designed to be provenance-friendly
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Created: 10/08/09 @ 13:31:07 | Last updated: 10/08/09 @ 13:32:21
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes in a document containg text and removes any non-ascii characters. The cleaned text is then sent to a service in Dresden, to extract all scientific terms. These terms represent a concept profile for the input concpet. Any null values are also removed.
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Created: 08/07/09 @ 16:26:13 | Last updated: 14/12/09 @ 11:59:14
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License: Creative Commons Attribution-No Derivative Works 3.0 Unported License
This workflow searches for genes which reside in a QTL (Quantitative Trait Loci) region in Arabidopsis thaliana. The workflow requires an input of: a chromosome name or number; a QTL start base pair position; QTL end base pair position. Data is then extracted from BioMart to annotate each of the genes found in this region. The UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to searcg for pathways in the KEGG pathway database.
...
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Created: 08/07/09 @ 16:28:34
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License: Creative Commons Attribution-No Derivative Works 3.0 Unported License
This workflow searches for genes which are found to be differentially expressed in a microarray study using Arabidopsis thaliana. The workflow requires an input of a list of differentially expressed AffyMetrix Probeset identifiers. Data is then extracted from BioMart to annotate each of the genes. The UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to searcg for pathways in the KEGG pathway database.
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Created: 19/08/09 @ 16:03:07
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow parses a KEGG species database into an Ondex Graph
graphId - the ID of the Graph.
inputDir - the plugin input directory
Species - Use this parameter to specify the species to be loaded from the kegg database. Default value is all.
ParseSequences - KEGG species code. Default value is false (boolean)
ImportOrthologFillers - Import Ortholog Pathway Fillers. Default value is false (boolean)
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Created: 20/11/09 @ 14:04:37 | Last updated: 20/11/09 @ 14:04:39
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow searches for genes which reside in a QTL (Quantitative Trait Loci) region in the Pig, Sus scrofa. The workflow requires an input of: a chromosome name or number; a QTL start base pair position; QTL end base pair position. Data is then extracted from BioMart to annotate each of the genes found in this region. The Entrez and UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to searcg for pathways in the KEGG pathway ...
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Created: 03/11/09 @ 04:29:15 | Last updated: 03/11/09 @ 04:29:19
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
test values:
query = paget disease
query = pdb4
query = hk1
query = h1n1
This rdfiser query those four federated search services EB-Eye, KEGG LinkDB, NCBI Entrez and UniProt knowledgebase. RDF triples are returned for search statistics with Bio2RDF normalised URIs.
This workflow should be used responsibly because it can generate high load at the provider resources.
test values:
query = paget disease
query = pdb4
query = hk1
query = h1n1
query = paget disease
query = pdb4
query = hk1
que...
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Created: 28/11/09 @ 18:06:16 | Last updated: 30/11/09 @ 20:17:03
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
TAG: knowledgescope, kegg, bio2rdf, banff_manifesto, rdf
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Created: 30/11/09 @ 20:44:13 | Last updated: 30/11/09 @ 20:44:55
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
Search all KEGG databases using bfind SOAP service and merge results into a bmuri list and a ntriples string.
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Created: 30/11/09 @ 21:38:23 | Last updated: 30/11/09 @ 21:44:57
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
No description
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Created: 30/11/09 @ 16:21:05 | Last updated: 30/11/09 @ 20:48:50
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow use KEGG's SOAP service provided to do a BFIND serch within one of the KEGG's official database. The results are returned in RDF ntriples format.
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Created: 10/03/10 @ 17:15:47 | Last updated: 10/03/10 @ 17:18:47
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow gets a series of information relating to a list of KEGG pathways supplied to it. It also removes any null values from a list of strings. Example input: path:mmu04010 path:mmu05014
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Created: 17/03/10 @ 10:53:02
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
Workflow takes in a text file of microRNAs from microCOSM (at the EBI) and outputs a list of KEGG pathway information, including genes in pathways and pathway abstracts from PubMed. The results can then be used in various text mining applications/workflows to rank the results against a given disease.Workflow takes in a file of microRNAs
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Created: 19/03/10 @ 13:46:37
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License: Creative Commons Attribution-No Derivative Works 3.0 Unported License
The KEGG pathway analysis of the workflow takes a list of UniProt accession numbers in any of the following formats with the following prefixes:
External database Database prefix
----------------- ---------------
NCBI GI ncbi-gi:
NCBI GeneID ncbi-geneid:
GenBank genbank:
UniGene unigene:
UniProt uniprot:
It performs this using the web service bconv, provided by the KEGG database (Kanehisa et a...
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Created: 19/03/10 @ 13:47:39 | Last updated: 19/03/10 @ 13:52:45
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
User inputs background and foreground colour to be used to highlight proteins in KEGG pathway image. User provides NCBI GI numbers. Worflow calculates KEGG ID and pathway ID and sends value to colour service, which adds colour to that KEGG id on pathway image. Also outputs kegg description, pathway description and url of image.
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Created: 19/03/10 @ 13:16:24 | Last updated: 19/03/10 @ 13:33:53
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
Takes GI number for source (non-pathogenic) and target (pathogneic) genomes, extracts list of all proteins from each genome using GenBank database. Outputs prtoeins in FastA format. Creates database from source proteins using formatdb (locally installed) and blasts (local installed) proteins from target against this database. Extracts protens which are unique (no blast hits) to the target (pathogenic) genome based on eValue set by user. Takes unique proteins from target and blasts aga...
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Created: 15/04/10 @ 12:22:12 | Last updated: 15/04/10 @ 12:22:13
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes in Entrez gene ids then adds the string "ncbi-geneid:" to the start of each gene id. These gene ids are then cross-referenced to KEGG gene ids. Each KEGG gene id is then sent to the KEGG pathway database and its relevant pathways returned.
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Created: 30/04/10 @ 16:09:29 | Last updated: 30/04/10 @ 16:12:02
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes a list of KEGG gene identifiers and supplies descriptions associated to said genes + pathways including all genes and the descriptions associated to said pathways.
The list_to_string local beanshell scripts merely transform a given list into a string of unique not-null elements separated by new lines (for batch btit use).
Note that the input is a real taverna list : multiple values must be declared as multiple values instead of a single string value with distinct identif...
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Created: 15/11/10 @ 12:08:18 | Last updated: 16/11/10 @ 16:07:49
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow searches for genes which reside in a QTL (Quantitative Trait Loci) region in the mouse, Mus musculus. The workflow requires an input of: a chromosome name or number; a QTL start base pair position; QTL end base pair position. Data is then extracted from BioMart to annotate each of the genes found in this region. The Entrez and UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to searcg for pathways in the KEGG path...
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Created: 15/11/10 @ 12:25:01 | Last updated: 15/11/10 @ 12:28:12
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow searches for genes which were found to be differentially expressed from a microarray study in the mouse, Mus musculus. The workflow requires an input of gene ref_seq identifiers. Data is then extracted from BioMart to annotate each of the genes found for each ref_seq id. The Entrez and UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to search for pathways in the KEGG pathway database.
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Created: 15/11/10 @ 12:30:21 | Last updated: 15/11/10 @ 12:30:59
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes in two lists of KEGG pathway ids. These are designed to come from pathways found from genes in a QTL (Quantitative Trait Loci) region, and from pathways found from genes differentially expressed in a microarray study. By identifying the intersecting pathways from both studies, a more informative picture is obtained of the candidate processes involved in the expression of a phenotype
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Created: 21/01/11 @ 16:56:47 | Last updated: 21/01/11 @ 16:58:50
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow searches for genes which reside in a QTL (Quantitative Trait Loci) region in Cow, Bos taurus. The workflow requires an input of: a chromosome name or number; a QTL start base pair position; QTL end base pair position. Data is then extracted from BioMart to annotate each of the genes found in this region. The Entrez and UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to searcg for pathways in the KEGG pathway data...
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Created: 08/02/11 @ 13:04:06 | Last updated: 10/02/11 @ 16:01:41
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes in a list of gene names and searches the PubMed database for corresponding articles. Any matches to the genes are then retrieved (abstracts only). These abstracts are then returned to the user.
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Created: 10/02/11 @ 16:10:52 | Last updated: 18/02/11 @ 13:47:08
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow takes in a list of gene names and KEGG pathway descriptions, and searches the PubMed database for corresponding articles. Any matches to the genes are then retrieved (abstracts only). These abstracts are then used to calculate a cosine vector space between two sets of corpora (gene and phenotype, or pathway and phenotype). The workflow counts the number of articles in the pubmed database in which each term occurs, and identifies the total number of articles in the entire PubMe...
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Created: 24/03/11 @ 15:14:48 | Last updated: 24/03/11 @ 15:37:48
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow searches for genes found from a set of differentially expressed probestes, in Human, Homo sapiens. The workflow requires an input human affymetrix probeset identifiers. Data is then extracted from BioMart to annotate each of the genes found in this region. The Entrez and UniProt identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to searcg for pathways in the KEGG pathway database.
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Created: 26/04/11 @ 14:50:37 | Last updated: 26/04/11 @ 15:04:28
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow allows the user to search for processes that are involved with a certain gene.
Using microarray-files (CEL-files), consisting of wild type and KO mice to which a stimulant is induced, the user can get an idea of the processes involved. (This is done using the global test and the literature weighted global test.) The results are then given as a text-file.
Warning: workflow is not working (needs some revisions), all input is currently hardcoded! (You will have to change the file...
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Created: 27/05/11 @ 11:06:11 | Last updated: 27/05/11 @ 11:06:52
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This workflow searches for genes which reside in a QTL (Quantitative Trait Loci) region in rice, Oryza sativa. The workflow requires an input of: a chromosome name or number; a QTL start base pair position; QTL end base pair position. Data is then extracted from BioMart to annotate each of the genes found in this region. The Entrez and UniGene identifiers are then sent to KEGG to obtain KEGG gene identifiers. The KEGG gene identifiers are then used to searcg for pathways in the KEGG pathway d...
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Created: 08/03/12 @ 11:47:39 | Last updated: 14/04/12 @ 15:14:49
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
Given a specific entrez gene id, returns the pathways that this gene participates in and for each of those pathways which genes are associated with. The workflow outputs also a KEGG pathway map and
the objects are colored according to the input color values.
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Created: 27/03/12 @ 10:52:31 | Last updated: 03/04/12 @ 09:20:02
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
Given a specific entrez gene id, returns the pathways that this gene participates in and for each of those pathways which genes (including their description) are associated with.
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Created: 29/09/08 @ 13:28:02 | Last updated: 08/10/08 @ 16:37:49
The pack contains a number of test workflows for kegg web service (and operations)
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Created: 10/08/09 @ 13:01:47 | Last updated: 11/08/09 @ 14:51:31
This pack contains a list of workflows and result files obtained from the analysis of candidate pathways believed to play a role in resistance to African Trypanosomiasis in the mouse model organism.
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Created: 08/12/10 @ 11:55:03 | Last updated: 01/02/11 @ 11:33:11
This pack contains workflows to navigate from candidate Quantitative Trait genes and pathways to a given phenotype.
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Created: 16/02/11 @ 12:49:21 | Last updated: 16/02/11 @ 15:26:36
This pack contains the workflows and data relating to Trichuriasis induced colitis.
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Created: 08/04/09 @ 18:06:23 | Last updated: 10/08/09 @ 12:10:07
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a list of KEGG gene descriptions, for each KEGG gene identified within the Tir1 QTL region.
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Created: 08/04/09 @ 19:23:53 | Last updated: 10/08/09 @ 12:08:00
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a list of KEGG gene identifiers, cross-referenced to UniProt and Entrez identifiers. The UniProt and Entrez ids were obtained from BioMart for genes located in the Tir1 QTL region.
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Created: 08/04/09 @ 19:25:05 | Last updated: 10/08/09 @ 12:06:18
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains the version of the KEGG pathway database used in the analysis of the Tir1 QTL region
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Created: 08/04/09 @ 19:27:55 | Last updated: 10/08/09 @ 11:29:34
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a list of KEGG pathway descriptions, identified from genes found within the Tir1 QTL region (for African Trypanosomiasis). Each pathway may contain multiple genes from within the QTL region.
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Created: 08/04/09 @ 19:28:52 | Last updated: 10/08/09 @ 11:03:00
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a list of KEGG pathway identifiers, derived from a list of Ensembl genes found to be located with a given QTL/chromosomal region in the mouse. These genes are located in the Tir1 QTL.
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Created: 10/08/09 @ 15:55:24
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This excel file contains a list of all pathways found to be differentially expressed at day 7 post infection in the trypanosomiasis resistance phenotype, which contain genes in the Tir1 QTL.
The pathways in this file have been ranked according to the scores obtained after calculating a cosine vector value against the trypanosomiasis resistance phenotype. The higher the score, the more closely linked to a phentype a given pathway is.
This allows each pathway to be ranked giving biologists a ...
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Created: 11/08/09 @ 14:08:41 | Last updated: 11/08/09 @ 14:15:58
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License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains all the abstracts for pathways found to be differentially expressed at day 7 post infection and intersect the Tir1 QTL region, from the African Trypanosomiasis project.
Each pathway is listed as ">> [Pathway Name]", together with a PubMed identifier, date, and abstract for each article. Each pathway has been restricted to 500 abstracts, and is given in the date range 31/12/2007 to 01/01/2009. Note, some pathways do not have any abstracts available due to th...
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Created: 01/04/11 @ 09:12:28 | Last updated: 01/04/11 @ 09:12:40
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Attributions: License: Creative Commons Attribution-Share Alike 3.0 Unported License
This file contains a list processed for Human gene expression CEL files relating to the: Impact of NRSF variant over-expression in SK-N-AS human neuroblastoma cells (http://www.ebi.ac.uk/arrayexpress/browse.html?keywords=E-GEOD-22467&expandefo=on).
The CEL files were analysed using the MADAT Taverna workflow available on myExperiment:
http://www.myexperiment.org/workflows/2002.html
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